The implication of the polymorphism of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease (CVD) patients treated with aspirin / Nur Jalinna Abdul Jalil

The implication of the polymorphism of COX-1, UGT1A6, and CYP2C9 among cardiovascular disease (CVD) patients treated with aspirin / Nur Jalinna Abdul Jalil

Acetylsalicylic acid (ASA) or aspirin is a pro-drug of salicylates which has significant effect in reducing the cardiovascular events. Potential polymorphic enzymes responsible for the pharmacokinetic variations of ASA include cyclooxygenase-l (COX-1) UDP—glucuronosyltransferase (UGT1A6) and P450 (C...

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Bibliographic Details
Main Author: Abdul Jalil, Nur Jalinna
Format: Thesis
Language:English
Published: 2014
Subjects:
Pharmaceutical dosage forms
Online Access:https://ir.uitm.edu.my/id/eprint/27272/

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