Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran

The study was aimed to determine the antifungal activity of Artocarpus altilis leaf extract and to compare the effectiveness of leaf extract in three different types of solvent (ethanol, chloroform and water). Antifungal activity was tested against four pathogenic fungi (Aspergillus fumigatus, Asper...

Full description

Bibliographic Details
Main Author: Boiran, Faridah
Format: Student Project
Language:English
Published: Faculty of Applied Sciences 2016
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/24431/
_version_ 1848805984154157056
author Boiran, Faridah
author_facet Boiran, Faridah
author_sort Boiran, Faridah
building UiTM Institutional Repository
collection Online Access
description The study was aimed to determine the antifungal activity of Artocarpus altilis leaf extract and to compare the effectiveness of leaf extract in three different types of solvent (ethanol, chloroform and water). Antifungal activity was tested against four pathogenic fungi (Aspergillus fumigatus, Aspergillus niger, Tricophyton sp and Malassezia sp) using disc diffusion method by indicating the presence of the clear zone of inhibition around discs impregnated with different concentration of extract (12.5, 25, 50 and 100 mg/ml). The positive control used was fluconazole and negative control was the solvent itself without extract. The result showed that water extract was the most effective compared to other solvents used (ethanol and chloroform) indicated by the highest inhibitory activity against the tested fungi. The only two fungi were inhibited (Aspergillus fumigatus and Aspergillus niger) at concentration 25, 50 and 100 mg/ml with concentration dependent manner. Aspergillus species were more susceptible as indicated by the largest diameter of inhibition zone at 13.33 mm of diameter against Aspergillus fumigatus followed by Aspergillus niger at 12.67 mm, while Tricophyton sp and Malassezia sp showed resistant to all different concentration of extracts. The result suggested that the Artocarpus altilis leaf extracts have the promising of low therapeutic potential against certain fungi.
first_indexed 2025-11-14T22:19:43Z
format Student Project
id uitm-24431
institution Universiti Teknologi MARA
institution_category Local University
language English
last_indexed 2025-11-14T22:19:43Z
publishDate 2016
publisher Faculty of Applied Sciences
recordtype eprints
repository_type Digital Repository
spelling uitm-244312019-06-20T06:13:32Z https://ir.uitm.edu.my/id/eprint/24431/ Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran Boiran, Faridah QR Microbiology Fungal antigens The study was aimed to determine the antifungal activity of Artocarpus altilis leaf extract and to compare the effectiveness of leaf extract in three different types of solvent (ethanol, chloroform and water). Antifungal activity was tested against four pathogenic fungi (Aspergillus fumigatus, Aspergillus niger, Tricophyton sp and Malassezia sp) using disc diffusion method by indicating the presence of the clear zone of inhibition around discs impregnated with different concentration of extract (12.5, 25, 50 and 100 mg/ml). The positive control used was fluconazole and negative control was the solvent itself without extract. The result showed that water extract was the most effective compared to other solvents used (ethanol and chloroform) indicated by the highest inhibitory activity against the tested fungi. The only two fungi were inhibited (Aspergillus fumigatus and Aspergillus niger) at concentration 25, 50 and 100 mg/ml with concentration dependent manner. Aspergillus species were more susceptible as indicated by the largest diameter of inhibition zone at 13.33 mm of diameter against Aspergillus fumigatus followed by Aspergillus niger at 12.67 mm, while Tricophyton sp and Malassezia sp showed resistant to all different concentration of extracts. The result suggested that the Artocarpus altilis leaf extracts have the promising of low therapeutic potential against certain fungi. Faculty of Applied Sciences 2016 Student Project NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/24431/1/PPb_FARIDAH%20BOIRAN%20AS%20N%2016_5.pdf Boiran, Faridah (2016) Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran. (2016) [Student Project] <http://terminalib.uitm.edu.my/24431.pdf> (Unpublished)
spellingShingle QR Microbiology
Fungal antigens
Boiran, Faridah
Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran
title Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran
title_full Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran
title_fullStr Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran
title_full_unstemmed Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran
title_short Antifungal activity of artocarpus altilis leaf extract / Faridah Boiran
title_sort antifungal activity of artocarpus altilis leaf extract / faridah boiran
topic QR Microbiology
Fungal antigens
url https://ir.uitm.edu.my/id/eprint/24431/