Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar
Three Schiff bases namely L1: MPD(ovan)₂, L2: triMe-MPD(ovan)₂ and L3: Cl-MPD(ovan)₂ are obtained from the condensation reaction between derivatives of m-phenylenediamine (MPD) with o-vanillin. Complexation with Co(II), Cu(II) and Zn(II) afford novel dinuclear complexes of dimeric nature. Their stru...
| Main Authors: | , , |
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| Format: | Research Reports |
| Language: | English |
| Published: |
Research Management Institute (RMI)
2011
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/23006/ |
| _version_ | 1848805639287996416 |
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| author | Bahron, Hadariah Kassim, Karimah Syed Omar, Sharifah Rohaiza |
| author_facet | Bahron, Hadariah Kassim, Karimah Syed Omar, Sharifah Rohaiza |
| author_sort | Bahron, Hadariah |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | Three Schiff bases namely L1: MPD(ovan)₂, L2: triMe-MPD(ovan)₂ and L3: Cl-MPD(ovan)₂ are obtained from the condensation reaction between derivatives of m-phenylenediamine (MPD) with o-vanillin. Complexation with Co(II), Cu(II) and Zn(II) afford novel dinuclear complexes of dimeric nature. Their structures are elucidated using various physicochemical techniques. The Schiff bases are indicated to act as tetradentate ligands in which both oxygen and nitrogen atoms serve as coordination sites for the metal ions. Antibacterial investigations revealed that the complexes are better bactericides than the parent ligands. The IC50 values against liver cells of the complexes are much lower than those of the parent ligands… |
| first_indexed | 2025-11-14T22:14:14Z |
| format | Research Reports |
| id | uitm-23006 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T22:14:14Z |
| publishDate | 2011 |
| publisher | Research Management Institute (RMI) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-230062020-03-20T14:58:51Z https://ir.uitm.edu.my/id/eprint/23006/ Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar Bahron, Hadariah Kassim, Karimah Syed Omar, Sharifah Rohaiza Bioactive compounds Three Schiff bases namely L1: MPD(ovan)₂, L2: triMe-MPD(ovan)₂ and L3: Cl-MPD(ovan)₂ are obtained from the condensation reaction between derivatives of m-phenylenediamine (MPD) with o-vanillin. Complexation with Co(II), Cu(II) and Zn(II) afford novel dinuclear complexes of dimeric nature. Their structures are elucidated using various physicochemical techniques. The Schiff bases are indicated to act as tetradentate ligands in which both oxygen and nitrogen atoms serve as coordination sites for the metal ions. Antibacterial investigations revealed that the complexes are better bactericides than the parent ligands. The IC50 values against liver cells of the complexes are much lower than those of the parent ligands… Research Management Institute (RMI) 2011 Research Reports NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/23006/1/LP_HADARIAH%20BAHRON%20RMI%2011_5.pdf Bahron, Hadariah and Kassim, Karimah and Syed Omar, Sharifah Rohaiza (2011) Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar. (2011) [Research Reports] (Unpublished) |
| spellingShingle | Bioactive compounds Bahron, Hadariah Kassim, Karimah Syed Omar, Sharifah Rohaiza Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar |
| title | Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar |
| title_full | Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar |
| title_fullStr | Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar |
| title_full_unstemmed | Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar |
| title_short | Multidentate azomethine series: complexation and bioactivity studies / Prof Dr Hadariah Bahron, Dr Karimah Kassim and Sharifah Rohaiza Syed Omar |
| title_sort | multidentate azomethine series: complexation and bioactivity studies / prof dr hadariah bahron, dr karimah kassim and sharifah rohaiza syed omar |
| topic | Bioactive compounds |
| url | https://ir.uitm.edu.my/id/eprint/23006/ |