Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir

Euphorbia hirta is a very popular herb amongst practitioners of traditional herb medicine, widely used as a decoction or infusion to treat various ailments including intestinal parasites, diarrhoea, vomiting, asthma, bronchitis, coughs and venereal diseases. The purpose of this study to find the...

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Main Author: Shahrir, Noramiera
Format: Student Project
Language:English
Published: Faculty of Applied Sciences 2017
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/22986/
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author Shahrir, Noramiera
author_facet Shahrir, Noramiera
author_sort Shahrir, Noramiera
building UiTM Institutional Repository
collection Online Access
description Euphorbia hirta is a very popular herb amongst practitioners of traditional herb medicine, widely used as a decoction or infusion to treat various ailments including intestinal parasites, diarrhoea, vomiting, asthma, bronchitis, coughs and venereal diseases. The purpose of this study to find the chemical compounds in E. hirta plant and also to perform antimicrobial study in order to determine the efficiency of E. hirta plants. The powdered plant material was extracted using two solvents methanol and hexane through sequential extraction. Agar well diffusion method was used to determine the antimicrobial activity against Escherichia coli and Candida albicans. The methanol produced the higher yield of. extract than hexane. Phytochemical screening of the crude extracts revealed the presence of alkaloid, flavonoid, terpenoids, tannins, phenolics and glycosides. Presense of bioactive constituents have been linked to the antimicrobial activity of the plant material. Methanol E. hirta extract is more effective in antibacterial than hexane extract. Different concentrations of crude extract show significant difference (P ≤ 0.05). E. hirta plants extract do not show any antifungal activity. The results presented in this study confirmed that extracts of E. hirta hold antibacterial potential effects against pathogenic microorganisms and therefore can be used as a safe, reliable and economical natural antibacterial source for therapeutic treatment.
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spelling uitm-229862019-02-01T02:37:47Z https://ir.uitm.edu.my/id/eprint/22986/ Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir Shahrir, Noramiera Polymers and polymer manufacture Biotechnology Euphorbia hirta is a very popular herb amongst practitioners of traditional herb medicine, widely used as a decoction or infusion to treat various ailments including intestinal parasites, diarrhoea, vomiting, asthma, bronchitis, coughs and venereal diseases. The purpose of this study to find the chemical compounds in E. hirta plant and also to perform antimicrobial study in order to determine the efficiency of E. hirta plants. The powdered plant material was extracted using two solvents methanol and hexane through sequential extraction. Agar well diffusion method was used to determine the antimicrobial activity against Escherichia coli and Candida albicans. The methanol produced the higher yield of. extract than hexane. Phytochemical screening of the crude extracts revealed the presence of alkaloid, flavonoid, terpenoids, tannins, phenolics and glycosides. Presense of bioactive constituents have been linked to the antimicrobial activity of the plant material. Methanol E. hirta extract is more effective in antibacterial than hexane extract. Different concentrations of crude extract show significant difference (P ≤ 0.05). E. hirta plants extract do not show any antifungal activity. The results presented in this study confirmed that extracts of E. hirta hold antibacterial potential effects against pathogenic microorganisms and therefore can be used as a safe, reliable and economical natural antibacterial source for therapeutic treatment. Faculty of Applied Sciences 2017 Student Project NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/22986/1/PPb_NORAMIERA%20SHAHRIR%20AS%20C%2017_5.PDF Shahrir, Noramiera (2017) Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir. (2017) [Student Project] <http://terminalib.uitm.edu.my/22986.pdf> (Unpublished)
spellingShingle Polymers and polymer manufacture
Biotechnology
Shahrir, Noramiera
Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir
title Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir
title_full Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir
title_fullStr Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir
title_full_unstemmed Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir
title_short Antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / Noramiera Shahrir
title_sort antimicrobial activity euphorbia hirta plant extracts against escherichia coli and candida albicans / noramiera shahrir
topic Polymers and polymer manufacture
Biotechnology
url https://ir.uitm.edu.my/id/eprint/22986/