Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman
Strobilanthes crispus also known as "Pokok pecah kaca" is a local herbs plant belong to family Acanthaceae. Synthetic drug had given the drawback and herbs plant can replaced the drug in term of medication. The leaves were selected because of its variety benefits in traditional folk med...
| Main Author: | |
|---|---|
| Format: | Student Project |
| Language: | English |
| Published: |
Faculty Of Applied Sciences
2017
|
| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/22910/ |
| _version_ | 1848805614100152320 |
|---|---|
| author | Muhamad Kamarazzaman, Nurfarahin |
| author_facet | Muhamad Kamarazzaman, Nurfarahin |
| author_sort | Muhamad Kamarazzaman, Nurfarahin |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | Strobilanthes crispus also known as "Pokok pecah kaca" is a local herbs plant
belong to family Acanthaceae. Synthetic drug had given the drawback and herbs
plant can replaced the drug in term of medication. The leaves were selected
because of its variety benefits in traditional folk medicine to treat diabetes and
anticancer treatment This study was done to determine the antimicrobial activity
against Gram Positive bacteria which were Staphylococcus aureus and Bacillus
subtilis, and Gram Negative bacteria which were Klebsiella pneumoniae and
Pseudomonas aeruginosa. This study also wants to investigate the phytochemical
compound that present in leaves of S.crispus. The minimal inhibitory
concentration (MIC) also been carried out. The antimicrobial activity of S.crispus
leaves extract against selected bacteria was tested at different concentrations using
disc diffusion method. Identification of the phytochemical compound was
determined through phytochemical screening. In methanol extract, the highest
antimicrobial activities were at 400mg/ml concentration against P.aeruginosa
with 12.67 mm of inhibition zone while, the lowest was against K.pneumoniae
with 8.66 mm of inhibition zone at 200mg/ml concentration. The leaves extract of
S.crispus in hexane solvent give no inhibition zone at all concentration in this
study. The phytochemical screening showed positive result for the presence of
flavonoid and saponins in both leaves extract. The MIC for methanol extract was
determined at 25mglml against P.aeruginosa. In conclusion, S.crispus leaves
extract showed the best potential to inhibit P.aeruginosa at 400mg/ml
concentration. Further investigation should be conducted on other species of
bacteria using other part of this plant. |
| first_indexed | 2025-11-14T22:13:50Z |
| format | Student Project |
| id | uitm-22910 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T22:13:50Z |
| publishDate | 2017 |
| publisher | Faculty Of Applied Sciences |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-229102019-01-23T00:44:27Z https://ir.uitm.edu.my/id/eprint/22910/ Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman Muhamad Kamarazzaman, Nurfarahin Physical plant physiology Botanical chemistry. Phytochemicals Strobilanthes crispus also known as "Pokok pecah kaca" is a local herbs plant belong to family Acanthaceae. Synthetic drug had given the drawback and herbs plant can replaced the drug in term of medication. The leaves were selected because of its variety benefits in traditional folk medicine to treat diabetes and anticancer treatment This study was done to determine the antimicrobial activity against Gram Positive bacteria which were Staphylococcus aureus and Bacillus subtilis, and Gram Negative bacteria which were Klebsiella pneumoniae and Pseudomonas aeruginosa. This study also wants to investigate the phytochemical compound that present in leaves of S.crispus. The minimal inhibitory concentration (MIC) also been carried out. The antimicrobial activity of S.crispus leaves extract against selected bacteria was tested at different concentrations using disc diffusion method. Identification of the phytochemical compound was determined through phytochemical screening. In methanol extract, the highest antimicrobial activities were at 400mg/ml concentration against P.aeruginosa with 12.67 mm of inhibition zone while, the lowest was against K.pneumoniae with 8.66 mm of inhibition zone at 200mg/ml concentration. The leaves extract of S.crispus in hexane solvent give no inhibition zone at all concentration in this study. The phytochemical screening showed positive result for the presence of flavonoid and saponins in both leaves extract. The MIC for methanol extract was determined at 25mglml against P.aeruginosa. In conclusion, S.crispus leaves extract showed the best potential to inhibit P.aeruginosa at 400mg/ml concentration. Further investigation should be conducted on other species of bacteria using other part of this plant. Faculty Of Applied Sciences 2017 Student Project NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/22910/1/PPb_NURFARAHIN%20MUHAMAD%20KAMARAZZAMAN%20AS%20C%2017_5.PDF Muhamad Kamarazzaman, Nurfarahin (2017) Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman. (2017) [Student Project] <http://terminalib.uitm.edu.my/22910.pdf> (Unpublished) |
| spellingShingle | Physical plant physiology Botanical chemistry. Phytochemicals Muhamad Kamarazzaman, Nurfarahin Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman |
| title | Phytochemical screening and antimicrobial activities of strobilanthes crispus against
selected bacteria / Nurfarahin Muhamad Kamarazzaman |
| title_full | Phytochemical screening and antimicrobial activities of strobilanthes crispus against
selected bacteria / Nurfarahin Muhamad Kamarazzaman |
| title_fullStr | Phytochemical screening and antimicrobial activities of strobilanthes crispus against
selected bacteria / Nurfarahin Muhamad Kamarazzaman |
| title_full_unstemmed | Phytochemical screening and antimicrobial activities of strobilanthes crispus against
selected bacteria / Nurfarahin Muhamad Kamarazzaman |
| title_short | Phytochemical screening and antimicrobial activities of strobilanthes crispus against
selected bacteria / Nurfarahin Muhamad Kamarazzaman |
| title_sort | phytochemical screening and antimicrobial activities of strobilanthes crispus against
selected bacteria / nurfarahin muhamad kamarazzaman |
| topic | Physical plant physiology Botanical chemistry. Phytochemicals |
| url | https://ir.uitm.edu.my/id/eprint/22910/ |