Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli

Sodium carboxymethylcellulose (SCMC) is widely used in the design of wound dressing owing to its high water bonding capacity, good compatibility with skin and mucous membrane, biocompatibility and abundant availability at a low cost. This study aims to design drug-free (low (LV), medium (MV) and hig...

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Main Author: Ramli, Nor Amlizan
Format: Book Section
Language:English
Published: Institute of Graduate Studies, UiTM 2014
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/19627/
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author Ramli, Nor Amlizan
author_facet Ramli, Nor Amlizan
author_sort Ramli, Nor Amlizan
building UiTM Institutional Repository
collection Online Access
description Sodium carboxymethylcellulose (SCMC) is widely used in the design of wound dressing owing to its high water bonding capacity, good compatibility with skin and mucous membrane, biocompatibility and abundant availability at a low cost. This study aims to design drug-free (low (LV), medium (MV) and high molecular weight (HV)) SCMC scaffolds and promote their ability to promote partial thickness burn wound healing via wound moist regulation and microbial burden control. In addition, SCMC scaffolds of distinct wound healing ability is incorporated with γ-tocotrienol as antioxidant therapeutic and has its wound healing property assessed against pure tocopherol and tocotrienol. SCMC scaffolds were prepared by means of solvent evaporation technique and their physicochemical properties namely, in vitro erosion, moisture affinity, morphology, tensile strength, polymer molecular weight and carboxymethyl substitution were investigated against partial thickness burn wound.
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format Book Section
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institution Universiti Teknologi MARA
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language English
last_indexed 2025-11-14T22:01:09Z
publishDate 2014
publisher Institute of Graduate Studies, UiTM
recordtype eprints
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spelling uitm-196272018-06-07T03:08:09Z https://ir.uitm.edu.my/id/eprint/19627/ Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli Ramli, Nor Amlizan Malaysia Sodium carboxymethylcellulose (SCMC) is widely used in the design of wound dressing owing to its high water bonding capacity, good compatibility with skin and mucous membrane, biocompatibility and abundant availability at a low cost. This study aims to design drug-free (low (LV), medium (MV) and high molecular weight (HV)) SCMC scaffolds and promote their ability to promote partial thickness burn wound healing via wound moist regulation and microbial burden control. In addition, SCMC scaffolds of distinct wound healing ability is incorporated with γ-tocotrienol as antioxidant therapeutic and has its wound healing property assessed against pure tocopherol and tocotrienol. SCMC scaffolds were prepared by means of solvent evaporation technique and their physicochemical properties namely, in vitro erosion, moisture affinity, morphology, tensile strength, polymer molecular weight and carboxymethyl substitution were investigated against partial thickness burn wound. Institute of Graduate Studies, UiTM 2014 Book Section PeerReviewed text en https://ir.uitm.edu.my/id/eprint/19627/1/ABS_NOR%20AMLIZAN%20RAMLI%20TDRA%20VOL%206%20IGS_14.pdf Ramli, Nor Amlizan (2014) Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli. (2014) In: The Doctoral Research Abstracts. IPSis Biannual Publication, 6 (6). Institute of Graduate Studies, UiTM, Shah Alam.
spellingShingle Malaysia
Ramli, Nor Amlizan
Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli
title Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli
title_full Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli
title_fullStr Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli
title_full_unstemmed Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli
title_short Carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / Nor Amlizan Ramli
title_sort carboxymethylcellulose scaffolds for treatment of partial thickness burn wound - the aspects of wound moist regulation, bacterial burden control and tocotrienol therapeutic / nor amlizan ramli
topic Malaysia
url https://ir.uitm.edu.my/id/eprint/19627/