Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak
Malay sub-ethnic groups in Peninsular Malaysia have a rich culture and tradition such as historical knowledge and heritage, which might be reflected in the current genetic makeup of this population. They are a mixture of different races that were caused by the history of migration centuries ago and...
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| Format: | Thesis |
| Language: | English |
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2015
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| Online Access: | https://ir.uitm.edu.my/id/eprint/15827/ |
| _version_ | 1848803848177582080 |
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| author | Abd. Razak, Muhd Shah Jehan |
| author_facet | Abd. Razak, Muhd Shah Jehan |
| author_sort | Abd. Razak, Muhd Shah Jehan |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | Malay sub-ethnic groups in Peninsular Malaysia have a rich culture and tradition such as historical knowledge and heritage, which might be reflected in the current genetic makeup of this population. They are a mixture of different races that were caused by the history of migration centuries ago and consisted of 14 Malay sub-ethnic groups in Peninsular Malaysia. The objective of this study was to analyze the genetic polymorphism of Y chromosome at DYS287 Y Alu Polymorphism (YAP) locus in six Malay sub-ethnic groups of Peninsular Malaysia. A total of 231 buccal cells from healthy unrelated individual males consisting of 117 Kelantan-Malay, 50 Jawa-Malay, 48 Minangkabau-Malay, 9 Banjar Malay, 3 Bugis-Malay and 4 Rao-Malay from different regions of Peninsular Malaysia were screened for the DYS287 Y Alu locus from their genomic DNA. It shows that Kelantan-Malay, Jawa-Malay, Minangkabau-Malay, Banjar-Malay, Bugis-Malay and Rao-Malayare completely absent of theDYS287 Y Alu Polymorphism. Sequence results revealed that all Malay sub-ethnic of Peninsular Malaysia groups studied do not carry the number of 45bp (long) and 28bp (short) with association of long adenine (A)residues at [poly(A) tail] of theAlu sequence at DYS287 locus. Allele frequency for YAP+ was absent in all Malay sub-ethnic groups in Peninsular Malaysia. They were no genetic differences between the studied Malay subethnic groups of DYS287 locus. This study has provided information on the pattern of DYS287 Y Alu Polymorphism in Kelantan-Malay, Jawa-Malay, Minangkabau-Malay, Banjar-Malay, Bugis-Malay and Rao-Malay sub-ethnic group in Peninsular Malaysia. Further study will be done on more samples of the other Malay sub-ethnic groups in
Peninsular Malaysia to determine more DYS287 Y Alu Polymorphism status. |
| first_indexed | 2025-11-14T21:45:46Z |
| format | Thesis |
| id | uitm-15827 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:45:46Z |
| publishDate | 2015 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-158272022-11-24T03:54:23Z https://ir.uitm.edu.my/id/eprint/15827/ Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak Abd. Razak, Muhd Shah Jehan QP Physiology Malay sub-ethnic groups in Peninsular Malaysia have a rich culture and tradition such as historical knowledge and heritage, which might be reflected in the current genetic makeup of this population. They are a mixture of different races that were caused by the history of migration centuries ago and consisted of 14 Malay sub-ethnic groups in Peninsular Malaysia. The objective of this study was to analyze the genetic polymorphism of Y chromosome at DYS287 Y Alu Polymorphism (YAP) locus in six Malay sub-ethnic groups of Peninsular Malaysia. A total of 231 buccal cells from healthy unrelated individual males consisting of 117 Kelantan-Malay, 50 Jawa-Malay, 48 Minangkabau-Malay, 9 Banjar Malay, 3 Bugis-Malay and 4 Rao-Malay from different regions of Peninsular Malaysia were screened for the DYS287 Y Alu locus from their genomic DNA. It shows that Kelantan-Malay, Jawa-Malay, Minangkabau-Malay, Banjar-Malay, Bugis-Malay and Rao-Malayare completely absent of theDYS287 Y Alu Polymorphism. Sequence results revealed that all Malay sub-ethnic of Peninsular Malaysia groups studied do not carry the number of 45bp (long) and 28bp (short) with association of long adenine (A)residues at [poly(A) tail] of theAlu sequence at DYS287 locus. Allele frequency for YAP+ was absent in all Malay sub-ethnic groups in Peninsular Malaysia. They were no genetic differences between the studied Malay subethnic groups of DYS287 locus. This study has provided information on the pattern of DYS287 Y Alu Polymorphism in Kelantan-Malay, Jawa-Malay, Minangkabau-Malay, Banjar-Malay, Bugis-Malay and Rao-Malay sub-ethnic group in Peninsular Malaysia. Further study will be done on more samples of the other Malay sub-ethnic groups in Peninsular Malaysia to determine more DYS287 Y Alu Polymorphism status. 2015-10 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/15827/2/15827.pdf Abd. Razak, Muhd Shah Jehan (2015) Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak. (2015) Masters thesis, thesis, Universiti Teknologi MARA. <http://terminalib.uitm.edu.my/15827.pdf> |
| spellingShingle | QP Physiology Abd. Razak, Muhd Shah Jehan Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak |
| title | Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak |
| title_full | Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak |
| title_fullStr | Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak |
| title_full_unstemmed | Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak |
| title_short | Yap (Y alu polymorphism) signature in six Malay sub-ethnic groups in Peninsular Malaysia / Muhd Shah Jehan Abd Razak |
| title_sort | yap (y alu polymorphism) signature in six malay sub-ethnic groups in peninsular malaysia / muhd shah jehan abd razak |
| topic | QP Physiology |
| url | https://ir.uitm.edu.my/id/eprint/15827/ |