Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]
A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4dichlorobenzyldithiocarbazate (S-2.4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(ll), nickel(ll), copper(ll), zinc(ll) and cadmium(ll) with this Schiff base hav...
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| Format: | Article |
| Language: | English |
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Research Management Institute (RMI)
2010
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| Online Access: | https://ir.uitm.edu.my/id/eprint/12939/ |
| _version_ | 1848803205227479040 |
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| author | Abdul Manan, Mohd Abdul Fatah Bahron, Hadariah Kassim, Karimah Muhamad, Mohd Asrul Hafiz Sayed Mohamad, Syed Nazmi |
| author_facet | Abdul Manan, Mohd Abdul Fatah Bahron, Hadariah Kassim, Karimah Muhamad, Mohd Asrul Hafiz Sayed Mohamad, Syed Nazmi |
| author_sort | Abdul Manan, Mohd Abdul Fatah |
| building | UiTM Institutional Repository |
| collection | Online Access |
| description | A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4dichlorobenzyldithiocarbazate (S-2.4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(ll), nickel(ll), copper(ll), zinc(ll) and cadmium(ll) with this Schiff base have been prepared and characterized using elemental analysis and various physico-chemical techniques. In the cobalt(ll) andnickel(II) complexes the SchifJbase behaves as a uninegatively charged tridentate nitrogen-oxygen-sulfur (NOS) chelating ligand, bonding through the azomethine nitrogen, thiolate sulfur and carbonylic oxygen of the isatin moiety. However. in the copper(ll), zinc(II) and cadmium(II) complexes the Schiff base behaves as a nitrogen-sulfur (NS) bidentate chelating ligand, bonding through the azomethine nitrogen and thiolate sulfur. The Schiff base and the metal complexes were evaluated with respect to antimicrobial activity, which was performed in reallion to two selected pathogenic microbials (Bacillus subtilis and Pseudomonas aeruginosa). It was observed that only the zinc Schiffbase complex exhibited strong activity against the Bacillus subtilis bacteria with an inhibition zone of 25 mm. |
| first_indexed | 2025-11-14T21:35:32Z |
| format | Article |
| id | uitm-12939 |
| institution | Universiti Teknologi MARA |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:35:32Z |
| publishDate | 2010 |
| publisher | Research Management Institute (RMI) |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | uitm-129392016-05-30T02:09:45Z https://ir.uitm.edu.my/id/eprint/12939/ Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.] srj Abdul Manan, Mohd Abdul Fatah Bahron, Hadariah Kassim, Karimah Muhamad, Mohd Asrul Hafiz Sayed Mohamad, Syed Nazmi Schiff bases Fluoropolymers Metal complexes. Layered double hydroxides A novel Schiff base containing nitrogen-oxygen-sulfur (NOS) donor atoms formed from the condensation reaction of S-2,4dichlorobenzyldithiocarbazate (S-2.4BDTC) with 5-fluroisatin has been synthesized. Complexes of cobalt(ll), nickel(ll), copper(ll), zinc(ll) and cadmium(ll) with this Schiff base have been prepared and characterized using elemental analysis and various physico-chemical techniques. In the cobalt(ll) andnickel(II) complexes the SchifJbase behaves as a uninegatively charged tridentate nitrogen-oxygen-sulfur (NOS) chelating ligand, bonding through the azomethine nitrogen, thiolate sulfur and carbonylic oxygen of the isatin moiety. However. in the copper(ll), zinc(II) and cadmium(II) complexes the Schiff base behaves as a nitrogen-sulfur (NS) bidentate chelating ligand, bonding through the azomethine nitrogen and thiolate sulfur. The Schiff base and the metal complexes were evaluated with respect to antimicrobial activity, which was performed in reallion to two selected pathogenic microbials (Bacillus subtilis and Pseudomonas aeruginosa). It was observed that only the zinc Schiffbase complex exhibited strong activity against the Bacillus subtilis bacteria with an inhibition zone of 25 mm. Research Management Institute (RMI) 2010 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/12939/1/AJ_MOHD%20ABDUL%20FATAH%20ABDUL%20MANAN%20SRJ%2010%201.pdf Abdul Manan, Mohd Abdul Fatah and Bahron, Hadariah and Kassim, Karimah and Muhamad, Mohd Asrul Hafiz and Sayed Mohamad, Syed Nazmi (2010) Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.]. (2010) Scientific Research Journal <https://ir.uitm.edu.my/view/publication/Scientific_Research_Journal.html>, 7 (2). pp. 67-90. ISSN 1675-7009 https://srj.uitm.edu.my/ |
| spellingShingle | Schiff bases Fluoropolymers Metal complexes. Layered double hydroxides Abdul Manan, Mohd Abdul Fatah Bahron, Hadariah Kassim, Karimah Muhamad, Mohd Asrul Hafiz Sayed Mohamad, Syed Nazmi Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.] |
| title | Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.] |
| title_full | Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.] |
| title_fullStr | Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.] |
| title_full_unstemmed | Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.] |
| title_short | Synthesis, characterization and biological activity of NitrogenOxygen-Sulfur (NOS) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / Mohd Abdul Fatah Abdul Manan ... [et al.] |
| title_sort | synthesis, characterization and biological activity of nitrogenoxygen-sulfur (nos) transition metal complexes derived from novel s-2,4-dichlorobenzyldithiocarbazate with 5-fluoroisatin / mohd abdul fatah abdul manan ... [et al.] |
| topic | Schiff bases Fluoropolymers Metal complexes. Layered double hydroxides |
| url | https://ir.uitm.edu.my/id/eprint/12939/ https://ir.uitm.edu.my/id/eprint/12939/ |