Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]

Sargassum polycystum is a species of brown algae (Phaeophyta). Some recent studies have found many uses of this algae, one of them is for medicine. In this study, crude hexane, dichloromethane and methanol extracts of Sargassum polycystum were tested for toxicity activity and screened for its princi...

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Main Authors: Daud, Norhayati, Mohd Noor, Nor Nafizah, Alimon, Hasimah, Abdul Rashid, Nursuhaidah
Format: Article
Language:English
Published: Universiti Teknologi MARA, Pulau Pinang 2015
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/11997/
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author Daud, Norhayati
Mohd Noor, Nor Nafizah
Alimon, Hasimah
Abdul Rashid, Nursuhaidah
author_facet Daud, Norhayati
Mohd Noor, Nor Nafizah
Alimon, Hasimah
Abdul Rashid, Nursuhaidah
author_sort Daud, Norhayati
building UiTM Institutional Repository
collection Online Access
description Sargassum polycystum is a species of brown algae (Phaeophyta). Some recent studies have found many uses of this algae, one of them is for medicine. In this study, crude hexane, dichloromethane and methanol extracts of Sargassum polycystum were tested for toxicity activity and screened for its principal chemical substances. The toxicity test was done using Brine Shrimp Lethality (BSL) test against Artemia salina Leach. The results of this study showed the LC50 value of methanol extract was 295.12 mgml-1, while both hexane and dichloromethane extracts were 275.42 mgml-1. The BSL test exhibited no significant toxicity against A.salina. Phytochemical screening shows S. polycystum contained non polar and polar components. As the conclusion, S. polycystum contained secondary metabolites that are not toxic to A. salina and they are not a potential source for toxicity.
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publishDate 2015
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spelling uitm-119972016-07-27T00:36:49Z https://ir.uitm.edu.my/id/eprint/11997/ Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.] Daud, Norhayati Mohd Noor, Nor Nafizah Alimon, Hasimah Abdul Rashid, Nursuhaidah Toxicity testing Sea. Marine ecology. Ocean ecology Sargassum polycystum is a species of brown algae (Phaeophyta). Some recent studies have found many uses of this algae, one of them is for medicine. In this study, crude hexane, dichloromethane and methanol extracts of Sargassum polycystum were tested for toxicity activity and screened for its principal chemical substances. The toxicity test was done using Brine Shrimp Lethality (BSL) test against Artemia salina Leach. The results of this study showed the LC50 value of methanol extract was 295.12 mgml-1, while both hexane and dichloromethane extracts were 275.42 mgml-1. The BSL test exhibited no significant toxicity against A.salina. Phytochemical screening shows S. polycystum contained non polar and polar components. As the conclusion, S. polycystum contained secondary metabolites that are not toxic to A. salina and they are not a potential source for toxicity. Universiti Teknologi MARA, Pulau Pinang 2015 Article PeerReviewed text en https://ir.uitm.edu.my/id/eprint/11997/1/AJ_NORHAYATI%20DAUD%20EAJ%2015.pdf Daud, Norhayati and Mohd Noor, Nor Nafizah and Alimon, Hasimah and Abdul Rashid, Nursuhaidah (2015) Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]. (2015) Esteem Academic Journal <https://ir.uitm.edu.my/view/publication/Esteem_Academic_Journal.html>, 11 (1). pp. 109-116. ISSN 1675-7939
spellingShingle Toxicity testing
Sea. Marine ecology. Ocean ecology
Daud, Norhayati
Mohd Noor, Nor Nafizah
Alimon, Hasimah
Abdul Rashid, Nursuhaidah
Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]
title Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]
title_full Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]
title_fullStr Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]
title_full_unstemmed Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]
title_short Preliminary toxicity test and phytochemical screening of Sargassum Polycystum crude extracts from marine macroalgae / Norhayati Daud ... [et al.]
title_sort preliminary toxicity test and phytochemical screening of sargassum polycystum crude extracts from marine macroalgae / norhayati daud ... [et al.]
topic Toxicity testing
Sea. Marine ecology. Ocean ecology
url https://ir.uitm.edu.my/id/eprint/11997/