1-(2-Hydroxyethyl)imidazolidine-2-thione
1-(2-Hydroxyethyl)imidazolidine-2-thione (1) was obtained as a product from an in situ reaction between N-(2-hydroxyethyl)ethylenediamine, carbon disulfide, potassium hydroxide, and di(4-fluorobenzyl)tin dichloride. Compound 1 was characterized by IR, UV, 1H, 13C{1H}, and 2D (COSY, NOESY, HSQC, and...
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| Format: | Article |
| Language: | English |
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MDPI
2018
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| Online Access: | http://eprints.sunway.edu.my/947/ http://eprints.sunway.edu.my/947/1/Tiekink%201-%282-Hydroxyethyl...%29molbank-2018-M1035.pdf |
| _version_ | 1848801934907015168 |
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| author | Lee, See Mun * Ainnul H. S. Azizan, * Tiekink, Edward R. T. * |
| author_facet | Lee, See Mun * Ainnul H. S. Azizan, * Tiekink, Edward R. T. * |
| author_sort | Lee, See Mun * |
| building | SU Institutional Repository |
| collection | Online Access |
| description | 1-(2-Hydroxyethyl)imidazolidine-2-thione (1) was obtained as a product from an in situ reaction between N-(2-hydroxyethyl)ethylenediamine, carbon disulfide, potassium hydroxide, and di(4-fluorobenzyl)tin dichloride. Compound 1 was characterized by IR, UV, 1H, 13C{1H}, and 2D (COSY, NOESY, HSQC, and HMBC) NMR spectroscopies. The cyclic molecular structure was confirmed by single crystal X-ray crystallography which showed the five-membered ring to
be non-planar and the π-electron density to be localized over the CN2S chromophore. In the crystal, thioamide–N–H . . . O(hydroxy) and hydroxy–O–H . . . S(thione) hydrogen bonds lead to supramolecular layers in the bc-plane. |
| first_indexed | 2025-11-14T21:15:21Z |
| format | Article |
| id | sunway-947 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:15:21Z |
| publishDate | 2018 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-9472020-10-07T08:56:37Z http://eprints.sunway.edu.my/947/ 1-(2-Hydroxyethyl)imidazolidine-2-thione Lee, See Mun * Ainnul H. S. Azizan, * Tiekink, Edward R. T. * QD Chemistry 1-(2-Hydroxyethyl)imidazolidine-2-thione (1) was obtained as a product from an in situ reaction between N-(2-hydroxyethyl)ethylenediamine, carbon disulfide, potassium hydroxide, and di(4-fluorobenzyl)tin dichloride. Compound 1 was characterized by IR, UV, 1H, 13C{1H}, and 2D (COSY, NOESY, HSQC, and HMBC) NMR spectroscopies. The cyclic molecular structure was confirmed by single crystal X-ray crystallography which showed the five-membered ring to be non-planar and the π-electron density to be localized over the CN2S chromophore. In the crystal, thioamide–N–H . . . O(hydroxy) and hydroxy–O–H . . . S(thione) hydrogen bonds lead to supramolecular layers in the bc-plane. MDPI 2018-12-03 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/947/1/Tiekink%201-%282-Hydroxyethyl...%29molbank-2018-M1035.pdf Lee, See Mun * and Ainnul H. S. Azizan, * and Tiekink, Edward R. T. * (2018) 1-(2-Hydroxyethyl)imidazolidine-2-thione. Molbank, 2018 (4). M1035. ISSN 1422-8599 http://doi.org/10.3390/M1035 doi:10.3390/M1035 |
| spellingShingle | QD Chemistry Lee, See Mun * Ainnul H. S. Azizan, * Tiekink, Edward R. T. * 1-(2-Hydroxyethyl)imidazolidine-2-thione |
| title | 1-(2-Hydroxyethyl)imidazolidine-2-thione |
| title_full | 1-(2-Hydroxyethyl)imidazolidine-2-thione |
| title_fullStr | 1-(2-Hydroxyethyl)imidazolidine-2-thione |
| title_full_unstemmed | 1-(2-Hydroxyethyl)imidazolidine-2-thione |
| title_short | 1-(2-Hydroxyethyl)imidazolidine-2-thione |
| title_sort | 1-(2-hydroxyethyl)imidazolidine-2-thione |
| topic | QD Chemistry |
| url | http://eprints.sunway.edu.my/947/ http://eprints.sunway.edu.my/947/ http://eprints.sunway.edu.my/947/ http://eprints.sunway.edu.my/947/1/Tiekink%201-%282-Hydroxyethyl...%29molbank-2018-M1035.pdf |