Quorum sensing: An imperative longevity weapon in bacteria
Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which secures survival of its species. Many QS bacteria produce and release autoinduce...
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Academic Journals
2018
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| Online Access: | http://eprints.sunway.edu.my/900/ http://eprints.sunway.edu.my/900/1/Chandrajit%20Quorum%20sensing.pdf |
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| author | Pawar, Shrikant Lahiri, Chandrajit * |
| author_facet | Pawar, Shrikant Lahiri, Chandrajit * |
| author_sort | Pawar, Shrikant |
| building | SU Institutional Repository |
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| description | Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which secures survival of its species. Many QS bacteria produce and release autoinducers like acyl-homoserine lactone-signaling molecules to regulate cell population density.
Different species of bacteria utilize different QS molecules to regulate its gene expression. A free-living
marine bacterium, Vibrio harveyi, uses two QS system to control the density-dependent expression of
bioluminescence (lux), commonly classified as sensor and autoinducer system. In Pseudomonas aeruginosa, QS not only controls virulence factor production but also biofilm formation. It is comprised two hierarchically organised systems, each consisting of an autoinducer synthetase (LasI/RhlI) and a corresponding regulator protein (LasR/RhlR). Biofilms produced by Pseudomonas, under control of QS, are ubiquitous in nature and contribute towards colonizations in patients of cystic fibrosis. Other organisms like Haemophilus influenzae and Streptococcus also utilize QS mechanism to control
virulence in otitis and endocarditic decay. Overall, QS plays a major role in controlling bacterial
economy. It is a simple, practical and effective mechanism of production and control. If the concentration of enzyme is critical, bacteria can sense it and perform a prompt activation or repression of certain target genes for controlling its environment. This review focuses on the QS mechanisms and their role in the survival of few important bacterial species. |
| first_indexed | 2025-11-14T21:15:11Z |
| format | Article |
| id | sunway-900 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:15:11Z |
| publishDate | 2018 |
| publisher | Academic Journals |
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| repository_type | Digital Repository |
| spelling | sunway-9002019-04-26T07:11:23Z http://eprints.sunway.edu.my/900/ Quorum sensing: An imperative longevity weapon in bacteria Pawar, Shrikant Lahiri, Chandrajit * QR Microbiology Bacterial cells exhibit a complex pattern of co-operative behaviour as shown by their capacity to communicate amongst each other. Quorum sensing (QS) is a generic term used for bacterial cell-to-cell communication which secures survival of its species. Many QS bacteria produce and release autoinducers like acyl-homoserine lactone-signaling molecules to regulate cell population density. Different species of bacteria utilize different QS molecules to regulate its gene expression. A free-living marine bacterium, Vibrio harveyi, uses two QS system to control the density-dependent expression of bioluminescence (lux), commonly classified as sensor and autoinducer system. In Pseudomonas aeruginosa, QS not only controls virulence factor production but also biofilm formation. It is comprised two hierarchically organised systems, each consisting of an autoinducer synthetase (LasI/RhlI) and a corresponding regulator protein (LasR/RhlR). Biofilms produced by Pseudomonas, under control of QS, are ubiquitous in nature and contribute towards colonizations in patients of cystic fibrosis. Other organisms like Haemophilus influenzae and Streptococcus also utilize QS mechanism to control virulence in otitis and endocarditic decay. Overall, QS plays a major role in controlling bacterial economy. It is a simple, practical and effective mechanism of production and control. If the concentration of enzyme is critical, bacteria can sense it and perform a prompt activation or repression of certain target genes for controlling its environment. This review focuses on the QS mechanisms and their role in the survival of few important bacterial species. Academic Journals 2018-01-05 Article PeerReviewed text en http://eprints.sunway.edu.my/900/1/Chandrajit%20Quorum%20sensing.pdf Pawar, Shrikant and Lahiri, Chandrajit * (2018) Quorum sensing: An imperative longevity weapon in bacteria. African Journal of Microbiology Research, 12 (4). pp. 96-104. ISSN 1996-0808 http://doi.org/10.5897/AJMR2017.8751 doi:10.5897/AJMR2017.8751 |
| spellingShingle | QR Microbiology Pawar, Shrikant Lahiri, Chandrajit * Quorum sensing: An imperative longevity weapon in bacteria |
| title | Quorum sensing: An imperative longevity weapon in bacteria |
| title_full | Quorum sensing: An imperative longevity weapon in bacteria |
| title_fullStr | Quorum sensing: An imperative longevity weapon in bacteria |
| title_full_unstemmed | Quorum sensing: An imperative longevity weapon in bacteria |
| title_short | Quorum sensing: An imperative longevity weapon in bacteria |
| title_sort | quorum sensing: an imperative longevity weapon in bacteria |
| topic | QR Microbiology |
| url | http://eprints.sunway.edu.my/900/ http://eprints.sunway.edu.my/900/ http://eprints.sunway.edu.my/900/ http://eprints.sunway.edu.my/900/1/Chandrajit%20Quorum%20sensing.pdf |