A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines

annulation of 1,3,5-triazine ring onto 5-aminopyrazole-4-carboxylates via a one-pot,multicomponent, microwave-assisted approach. The products were obtained in good yields and high purity. This catalyst-free method was demonstrated to be scalable and highly reproducible in different microwave reacto...

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Main Authors: Lim, Felicia Phei Lin, Halcovitch, Nathan R., Tiekink, Edward R. T. *, Dolzhenko, Anton V
Format: Article
Language:English
Published: Elsevier 2018
Subjects:
Online Access:http://eprints.sunway.edu.my/790/
http://eprints.sunway.edu.my/790/1/Tiekink%20E%20A%20New%20microwave%20assisted.pdf
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author Lim, Felicia Phei Lin
Halcovitch, Nathan R.
Tiekink, Edward R. T. *
Dolzhenko, Anton V
author_facet Lim, Felicia Phei Lin
Halcovitch, Nathan R.
Tiekink, Edward R. T. *
Dolzhenko, Anton V
author_sort Lim, Felicia Phei Lin
building SU Institutional Repository
collection Online Access
description annulation of 1,3,5-triazine ring onto 5-aminopyrazole-4-carboxylates via a one-pot,multicomponent, microwave-assisted approach. The products were obtained in good yields and high purity. This catalyst-free method was demonstrated to be scalable and highly reproducible in different microwave reactors. Some structural features of the prepared compounds were studied in details using dynamic NMR spectroscopy and X-ray crystallography.
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institution Sunway University
institution_category Local University
language English
last_indexed 2025-11-14T21:14:44Z
publishDate 2018
publisher Elsevier
recordtype eprints
repository_type Digital Repository
spelling sunway-7902020-10-07T09:06:55Z http://eprints.sunway.edu.my/790/ A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines Lim, Felicia Phei Lin Halcovitch, Nathan R. Tiekink, Edward R. T. * Dolzhenko, Anton V QD Chemistry annulation of 1,3,5-triazine ring onto 5-aminopyrazole-4-carboxylates via a one-pot,multicomponent, microwave-assisted approach. The products were obtained in good yields and high purity. This catalyst-free method was demonstrated to be scalable and highly reproducible in different microwave reactors. Some structural features of the prepared compounds were studied in details using dynamic NMR spectroscopy and X-ray crystallography. Elsevier 2018-04-12 Article PeerReviewed text en http://eprints.sunway.edu.my/790/1/Tiekink%20E%20A%20New%20microwave%20assisted.pdf Lim, Felicia Phei Lin and Halcovitch, Nathan R. and Tiekink, Edward R. T. * and Dolzhenko, Anton V (2018) A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines. Tetrahedron, 74 (15). pp. 1868-1879. ISSN 0040-4020
spellingShingle QD Chemistry
Lim, Felicia Phei Lin
Halcovitch, Nathan R.
Tiekink, Edward R. T. *
Dolzhenko, Anton V
A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines
title A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines
title_full A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines
title_fullStr A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines
title_full_unstemmed A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines
title_short A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines
title_sort new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates:selective synthesis of substituted 5-aza-9-deaza-adenines
topic QD Chemistry
url http://eprints.sunway.edu.my/790/
http://eprints.sunway.edu.my/790/1/Tiekink%20E%20A%20New%20microwave%20assisted.pdf