Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis

The crystal structure analysis of three aryl-1,3-dithiane derivatives, with aryl=4-methylphenyl (1), 4-chlorophenyl (2) and 2,4-dichlorophenyl (3), shows the three molecules to have very similar conformations, with the aryl ring lying on an approximate mirror plane that bisects the dithiane ring whi...

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Main Authors: Zukerman-Schpector, Julio, Sousa Madureira, Lucas, Stefani, Hélio A., Gozhina, Olga, Tiekink, Edward R. T. *
Format: Article
Language:English
Published: De Gruyter 2016
Subjects:
Online Access:http://eprints.sunway.edu.my/655/
http://eprints.sunway.edu.my/655/1/Z.%20Kristallogr.%202016%20231%20329.pdf
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author Zukerman-Schpector, Julio
Sousa Madureira, Lucas
Stefani, Hélio A.
Gozhina, Olga
Tiekink, Edward R. T. *
author_facet Zukerman-Schpector, Julio
Sousa Madureira, Lucas
Stefani, Hélio A.
Gozhina, Olga
Tiekink, Edward R. T. *
author_sort Zukerman-Schpector, Julio
building SU Institutional Repository
collection Online Access
description The crystal structure analysis of three aryl-1,3-dithiane derivatives, with aryl=4-methylphenyl (1), 4-chlorophenyl (2) and 2,4-dichlorophenyl (3), shows the three molecules to have very similar conformations, with the aryl ring lying on an approximate mirror plane that bisects the dithiane ring which adopts a chair conformation; the energy-minimised structures are consistent with the experimental structures. The greater barrier to rotation about the methine-C–C(ipso) bond in 3, cf. 1 and 2, is related to unfavourable intramolecular S···Cl interactions in the putative transition state. The molecular packing in 1–3, while globally similar, are distinct, being based on combinations of identifiable C–H···π(arene), C–H···S and C–Cl···π(arene) interactions. The lack of isostructural relationships points to the significance of the identified intermolecular interactions to direct molecular packing.
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spelling sunway-6552020-10-07T10:02:40Z http://eprints.sunway.edu.my/655/ Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis Zukerman-Schpector, Julio Sousa Madureira, Lucas Stefani, Hélio A. Gozhina, Olga Tiekink, Edward R. T. * QD Chemistry The crystal structure analysis of three aryl-1,3-dithiane derivatives, with aryl=4-methylphenyl (1), 4-chlorophenyl (2) and 2,4-dichlorophenyl (3), shows the three molecules to have very similar conformations, with the aryl ring lying on an approximate mirror plane that bisects the dithiane ring which adopts a chair conformation; the energy-minimised structures are consistent with the experimental structures. The greater barrier to rotation about the methine-C–C(ipso) bond in 3, cf. 1 and 2, is related to unfavourable intramolecular S···Cl interactions in the putative transition state. The molecular packing in 1–3, while globally similar, are distinct, being based on combinations of identifiable C–H···π(arene), C–H···S and C–Cl···π(arene) interactions. The lack of isostructural relationships points to the significance of the identified intermolecular interactions to direct molecular packing. De Gruyter 2016 Article PeerReviewed text en http://eprints.sunway.edu.my/655/1/Z.%20Kristallogr.%202016%20231%20329.pdf Zukerman-Schpector, Julio and Sousa Madureira, Lucas and Stefani, Hélio A. and Gozhina, Olga and Tiekink, Edward R. T. * (2016) Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis. Zeitschrift für Kristallographie - Crystalline Materials, 231 (6). pp. 329-339. ISSN 2194-4946 http://dx.doi.org/10.1515/zkri-2015-1911 doi:10.1515/zkri-2015-1911
spellingShingle QD Chemistry
Zukerman-Schpector, Julio
Sousa Madureira, Lucas
Stefani, Hélio A.
Gozhina, Olga
Tiekink, Edward R. T. *
Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis
title Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis
title_full Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis
title_fullStr Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis
title_full_unstemmed Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis
title_short Structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and Hirshfeld surface analysis
title_sort structural systematics of aryl-1,3-dithiane derivatives: crystal and energy-minimised structures, and hirshfeld surface analysis
topic QD Chemistry
url http://eprints.sunway.edu.my/655/
http://eprints.sunway.edu.my/655/
http://eprints.sunway.edu.my/655/
http://eprints.sunway.edu.my/655/1/Z.%20Kristallogr.%202016%20231%20329.pdf