Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s)
Despite advances in in therapeutic interventions and supportive care, the morbidity and mortality associated with cancer has remained significant. Thus there is a need for newer and more powerful anti-tumour agents. The search for new anti-tumour compounds originating from natural resources is a pro...
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| Format: | Article |
| Language: | English |
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American Chemical Society
2017
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| Online Access: | http://eprints.sunway.edu.my/531/ http://eprints.sunway.edu.my/531/1/Naveed%20Khan%20Anticancer%20Agents%20from%20animals.pdf |
| _version_ | 1848801839856746496 |
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| author | Jeyamogan, Shareni Khan, Naveed Ahmed * Siddiqui, Ruqaiyyah Bano * |
| author_facet | Jeyamogan, Shareni Khan, Naveed Ahmed * Siddiqui, Ruqaiyyah Bano * |
| author_sort | Jeyamogan, Shareni |
| building | SU Institutional Repository |
| collection | Online Access |
| description | Despite advances in in therapeutic interventions and supportive care, the morbidity and mortality associated with cancer has remained significant. Thus there is a need for newer and more powerful anti-tumour agents. The search for new anti-tumour compounds originating from natural resources is a promising research area. Animals living in polluted environments are a potent source of anti-tumour agents. Under polluted milieus, species such as crocodiles, feed on rotten meat, are exposed to heavy metals, endure high levels of radiation, are among the very few species to survive the catastrophic Cretaceous-Tertiary extinction event with a prolonged lifespan. Thus it is reasonable to speculate that animals such as crocodiles have developed mechanisms to defend themselves against cancer. The discovery of antitumor activity in animals such as crocodiles, whales, sharks, etc will stimulate research in finding therapeutic molecules from unusual sources, and has potential for the development of novel antitumor compound(s) that may also overcome current drug resistance. Nevertheless, intensive research in the next few years will be required to realize these expectations. |
| first_indexed | 2025-11-14T21:13:50Z |
| format | Article |
| id | sunway-531 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:13:50Z |
| publishDate | 2017 |
| publisher | American Chemical Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-5312019-07-03T08:31:59Z http://eprints.sunway.edu.my/531/ Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) Jeyamogan, Shareni Khan, Naveed Ahmed * Siddiqui, Ruqaiyyah Bano * QH301 Biology Despite advances in in therapeutic interventions and supportive care, the morbidity and mortality associated with cancer has remained significant. Thus there is a need for newer and more powerful anti-tumour agents. The search for new anti-tumour compounds originating from natural resources is a promising research area. Animals living in polluted environments are a potent source of anti-tumour agents. Under polluted milieus, species such as crocodiles, feed on rotten meat, are exposed to heavy metals, endure high levels of radiation, are among the very few species to survive the catastrophic Cretaceous-Tertiary extinction event with a prolonged lifespan. Thus it is reasonable to speculate that animals such as crocodiles have developed mechanisms to defend themselves against cancer. The discovery of antitumor activity in animals such as crocodiles, whales, sharks, etc will stimulate research in finding therapeutic molecules from unusual sources, and has potential for the development of novel antitumor compound(s) that may also overcome current drug resistance. Nevertheless, intensive research in the next few years will be required to realize these expectations. American Chemical Society 2017 Article PeerReviewed text en http://eprints.sunway.edu.my/531/1/Naveed%20Khan%20Anticancer%20Agents%20from%20animals.pdf Jeyamogan, Shareni and Khan, Naveed Ahmed * and Siddiqui, Ruqaiyyah Bano * (2017) Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s). ACS Chemical Neuroscience. ISSN 1948-7193 https://ncbi.nlm.nih.gov/pubmed/28795217 |
| spellingShingle | QH301 Biology Jeyamogan, Shareni Khan, Naveed Ahmed * Siddiqui, Ruqaiyyah Bano * Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) |
| title | Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) |
| title_full | Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) |
| title_fullStr | Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) |
| title_full_unstemmed | Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) |
| title_short | Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) |
| title_sort | animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) |
| topic | QH301 Biology |
| url | http://eprints.sunway.edu.my/531/ http://eprints.sunway.edu.my/531/ http://eprints.sunway.edu.my/531/1/Naveed%20Khan%20Anticancer%20Agents%20from%20animals.pdf |