Targeting brain-eating amoebae infections
Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2017
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| Online Access: | http://eprints.sunway.edu.my/485/ http://eprints.sunway.edu.my/485/1/Targeting%20brain%20eating%20amoebae%20infections.pdf |
| _version_ | 1848801830165807104 |
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| author | Khan, Naveed Ahmed * Ong, Timothy Yu Yee * Siddiqui, Ruqaiyyah Bano * |
| author_facet | Khan, Naveed Ahmed * Ong, Timothy Yu Yee * Siddiqui, Ruqaiyyah Bano * |
| author_sort | Khan, Naveed Ahmed * |
| building | SU Institutional Repository |
| collection | Online Access |
| description | Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite viability without affecting the host cells, with an eye to improve formulation of drugs and/or administration of drugs against brain-eating amoebae. |
| first_indexed | 2025-11-14T21:13:41Z |
| format | Article |
| id | sunway-485 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:13:41Z |
| publishDate | 2017 |
| publisher | American Chemical Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-4852020-01-23T03:28:08Z http://eprints.sunway.edu.my/485/ Targeting brain-eating amoebae infections Khan, Naveed Ahmed * Ong, Timothy Yu Yee * Siddiqui, Ruqaiyyah Bano * Q Science (General) QR355 Virology Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite viability without affecting the host cells, with an eye to improve formulation of drugs and/or administration of drugs against brain-eating amoebae. American Chemical Society 2017-02-22 Article PeerReviewed text en http://eprints.sunway.edu.my/485/1/Targeting%20brain%20eating%20amoebae%20infections.pdf Khan, Naveed Ahmed * and Ong, Timothy Yu Yee * and Siddiqui, Ruqaiyyah Bano * (2017) Targeting brain-eating amoebae infections. ACS Chemical Neuroscience, 8 (4). pp. 687-688. ISSN 1948-7193 http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.7b00049 DOI: 10.1021/acschemneuro.7b00049 |
| spellingShingle | Q Science (General) QR355 Virology Khan, Naveed Ahmed * Ong, Timothy Yu Yee * Siddiqui, Ruqaiyyah Bano * Targeting brain-eating amoebae infections |
| title | Targeting brain-eating amoebae infections |
| title_full | Targeting brain-eating amoebae infections |
| title_fullStr | Targeting brain-eating amoebae infections |
| title_full_unstemmed | Targeting brain-eating amoebae infections |
| title_short | Targeting brain-eating amoebae infections |
| title_sort | targeting brain-eating amoebae infections |
| topic | Q Science (General) QR355 Virology |
| url | http://eprints.sunway.edu.my/485/ http://eprints.sunway.edu.my/485/ http://eprints.sunway.edu.my/485/ http://eprints.sunway.edu.my/485/1/Targeting%20brain%20eating%20amoebae%20infections.pdf |