Neural differentiation of human pluripotent stem cells for nontherapeutic applications: Toxicology, pharmacology, and in vitro disease modelling [Review article].

QR Code

Neural differentiation of human pluripotent stem cells for nontherapeutic applications: Toxicology, pharmacology, and in vitro disease modelling [Review article].

Human pluripotent stem cells (hPSCs) derived from either blastocyst stage embryos (hESCs) or reprogrammed somatic cells (iPSCs) can provide an abundant source of human neuronal lineages that were previously sourced from human cadavers, abortuses, and discarded surgical waste. In addition to the well...

Full description

Bibliographic Details
Main Authors:	Yap, May Shin , Nathan, Kavitha R. , Yeo, Yin , Lim, Lee Wei, Poh, Chit Laa , Richards, Mark, Lim, Wei Ling , Othman, Lekhsan, Heng, Alexis Boon Chin
Format:	Article
Language:	English
Published:	Hindawi Publishing Corporation 2015
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://eprints.sunway.edu.my/395/ http://eprints.sunway.edu.my/395/1/Neural%20Differentiation%20of%20Human%20Pluripotent%20Stem%20Cells.pdf

Similar Items

Pluripotent human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy
by: Yap, May Shin *, et al.
Published: (2016)

Strategies to improve the physicochemical properties of peptide‑based drugs
by: Lee, Michelle Felicia *, et al.
Published: (2023)

Toxicological profiles of Carbamazepine, Gabapentin and their combination at high therapeutic doses in rat
by: Abdullah, Sinan Mohammed, et al.
Published: (2014)

Rhodomyrtus Tomentosa: A Phytochemical and Pharmacological Review
by: Hazrulrizawati, Hamid, et al.
Published: (2017)

Isolation,Characterization And Preliminary Pharmacological Evaluation Of Constituents Of Garcinia Cowa Roxb
by: Sri Wahyuni, Fatma
Published: (2009)

In vitro evaluation of the antiviral activity of heparan sulfate mimetic compounds against Enterovirus 71
by: Pourianfar, Hamid Reza, et al.
Published: (2012)

Ethnobotanical, phytochemical, pharmacological, and toxicological aspects of Persicaria hydropiper (L.) Delarbre
by: Moyeenul Huq, A. K. M., et al.
Published: (2014)

Proteomic analysis and pharmacological activities of the venom of the Moroccan cobra Naja haje legionis
by: Malih, Ibitissam, et al.
Published: (2012)

A review of ethnobotany, phytochemistry, antimicrobial pharmacology and toxicology of Nigella sativa L.
by: Hossain, Md. Sanower, et al.
Published: (2021)

Phytochemical screening and anti-cancer effect of Clinacanthus nutans extract towards cervical cancer cell line, HeLa
by: Yee, Lim Wei
Published: (2013)

Automated electrophysiological and pharmacological evaluation of human pluripotent stem cell-derived cardiomyocytes
by: Rajamohan, Divya, et al.
Published: (2016)

A concise review of extraction and characterization of chondroitin sulphate from fish and fish wastes for pharmacological application
by: Urbi, Zannat, et al.
Published: (2022)

Murdannia loriformis: a review of ethnomedicinal uses, phytochemistry, pharmacology, contemporary application, and toxicology
by: Che Sulaiman, Intan Soraya, et al.
Published: (2021)

Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review
by: Zainol, Haida, et al.
Published: (2022)

Non-pharmacological management of fever in otherwise healthy children
by: Watts, Robin, et al.
Published: (2012)

Recent topics of pharmacology in oriental medicine : detoxification of morphine addiction in the mouse narcotic dependence model using extracts from psidium guajava leaves
by: Lutterodt, George Daniel
Published: (1999)

Pharmacological relevance of primitive leafy Cactuses Pereskia
by: M., Sharif K., et al.
Published: (2013)

Isolation and pharmacological characterization of a short neurotoxin, α-elapitoxin-Bf1b (α-EPTX-Bf1b) from Malaysian Bungarus fasciatus
by: Ahmad Rusmili, Muhamad Rusdi, et al.
Published: (2013)

Usnic acid as potential inhibitors of BCL2 and P13K protein through network pharmacology-based analysis, molecular docking and molecular dynamic simulation
by: Wong, K. K. V., et al.
Published: (2023)

Pharmacological and toxicological effects of 6-hydroxy-2-mercaptopurine and 6-thioguanine in in vitro and in vivo models of arthritis
by: Nordin, Nurul Syuhada
Published: (2021)

Cross-reactive neutralizing antibody epitopes against Enterovirus 71 identified by an in silico approach
by: Kirk, Kristin, et al.
Published: (2012)

A review of standard pharmacological therapy for adult asthma - Steps 1 to 5
by: Patel, Mitesh Dilipkumar Kantilal, et al.
Published: (2015)

Melodinus eugeniifolius. (apocynaceae juss.): a phytochemical and pharmacological study
by: Lu, Yao
Published: (2016)

Inhibition of Enterovirus 71 (EV-71 infections by a novel antiviral peptide derived from EV-71 capsid protein VP1
by: Tan, Chee Wah, et al.
Published: (2012)

Toxinological and pharmacological characterization of Southeast Asian Naja kaouthia (Monocled cobra) venom /Tan Kae Yi
by: Tan, Kae Yi
Published: (2016)

Health Benefits and Pharmacological Properties of Stigmasterol
by: Saad, Bakrim, et al.
Published: (2022)

Pharmacological effects of paeonol against endoplasmic reticulum stress and inflammation-induced endothelial dysfunction / Choy Ker Woon
by: Choy, Ker Woon
Published: (2018)

Identifying key elements of non-pharmacological treatment package for fibromyalgia: Evidence synthesis and Delphi exercise
by: Kundakci, Burak
Published: (2021)

Stachytarpheta jamaicensis (L.) Vahl: from traditional usage to pharmacological evidence
by: Liew, Pearl Majorie, et al.
Published: (2016)

Identification of molecular determinants of cell culture growth characteristics of Enterovirus 71
by: Yee, Isabel Pin Tsin *, et al.
Published: (2016)

Pharmacological importance of TG12 from tachykinin and its toxicological behavior against multidrug-resistant bacteria Klebsiella pneumonia
by: Raju, Stefi V., et al.
Published: (2021)

Effect of scapular retraction exercise on forward head posture among university students
by: Tay, Kai Wei
Published: (2022)

Relationship between quadriceps angle and hamstring flexibility with knee injuries among weight lifters in Selangor, Malaysia
by: Teh, Wei Ze
Published: (2022)

Design, synthesis and pharmacological evaluation of novel fluorescent ligands for the mu-opioid receptor
by: Marshall, William
Published: (2021)

Development of dengue vaccines
by: Lim, Chee Siean *, et al.
Published: (2018)

Insights into innate and adaptive immune responses in vaccine development against EV-A71
by: Lim, Hui Xuan *, et al.
Published: (2019)

Development of antivirals and vaccines against enterovirus 71 (EV-A71)
by: Poh, Chit Laa *
Published: (2018)

Phytochemical and pharmacological profile of Kaduk (Piper sarmentosum Roxb.)
by: Ghazali, Nor Farahiyah, et al.
Published: (2018)

Estrogenic post-menopausal anti-osteoporotic mechanism of Achyranthes aspera L.: Phytochemicals and network pharmacology approaches
by: Moyeenul Huq, A. K. M., et al.
Published: (2024)

Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches
by: Roney, Miah, et al.
Published: (2025)