Investigation of the effect of 131I on blood parameters for thyroid cancer treatment

Hematopoiesis plays a significant role in mammals’ life. Hematopoietic damage due to radiations of different arrays, such as ionizing and non-ionizing radiations, could lead to external infections, internal infections, and anemia. Different cancers’ treatment using radioactive sources affects the bl...

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Main Authors: Khandaker, Mayeen Uddin *, Hassanpour, Mehdi, Khezripour, Saeedeh, Rezaei, Mohammad Reza, Bazghandi, Atefeh, Hassanpour, Marzieh, Faruque, Mohammad Rashed Iqbal, Bradley, D.A. *
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Published: Elsevier 2023
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Online Access:http://eprints.sunway.edu.my/2256/
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author Khandaker, Mayeen Uddin *
Hassanpour, Mehdi
Khezripour, Saeedeh
Rezaei, Mohammad Reza
Bazghandi, Atefeh
Hassanpour, Marzieh
Faruque, Mohammad Rashed Iqbal
Bradley, D.A. *
author_facet Khandaker, Mayeen Uddin *
Hassanpour, Mehdi
Khezripour, Saeedeh
Rezaei, Mohammad Reza
Bazghandi, Atefeh
Hassanpour, Marzieh
Faruque, Mohammad Rashed Iqbal
Bradley, D.A. *
author_sort Khandaker, Mayeen Uddin *
building SU Institutional Repository
collection Online Access
description Hematopoiesis plays a significant role in mammals’ life. Hematopoietic damage due to radiations of different arrays, such as ionizing and non-ionizing radiations, could lead to external infections, internal infections, and anemia. Different cancers’ treatment using radioactive sources affects the blood parameters (i.e., mature cells, immature cells, and stem cells). In the present paper, the effect of intravascular injection of Iodine-131 (131I) on the blood parameters for thyroid cancer treatment has been investigated utilizing the MCNPX code and Runge-Kutta fourth-order method. The simulation results showed that the accumulated absorbed dose in adult phantom (ORNL whole body phantom) due to normalized intravascular injection of 1 mCi (mCi) of 131I was 1.97 × 10
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publishDate 2023
publisher Elsevier
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spelling sunway-22562023-06-16T03:48:58Z http://eprints.sunway.edu.my/2256/ Investigation of the effect of 131I on blood parameters for thyroid cancer treatment Khandaker, Mayeen Uddin * Hassanpour, Mehdi Khezripour, Saeedeh Rezaei, Mohammad Reza Bazghandi, Atefeh Hassanpour, Marzieh Faruque, Mohammad Rashed Iqbal Bradley, D.A. * QA Mathematics QC Physics QP Physiology RC Internal medicine Hematopoiesis plays a significant role in mammals’ life. Hematopoietic damage due to radiations of different arrays, such as ionizing and non-ionizing radiations, could lead to external infections, internal infections, and anemia. Different cancers’ treatment using radioactive sources affects the blood parameters (i.e., mature cells, immature cells, and stem cells). In the present paper, the effect of intravascular injection of Iodine-131 (131I) on the blood parameters for thyroid cancer treatment has been investigated utilizing the MCNPX code and Runge-Kutta fourth-order method. The simulation results showed that the accumulated absorbed dose in adult phantom (ORNL whole body phantom) due to normalized intravascular injection of 1 mCi (mCi) of 131I was 1.97 × 10 Elsevier 2023-07 Article PeerReviewed Khandaker, Mayeen Uddin * and Hassanpour, Mehdi and Khezripour, Saeedeh and Rezaei, Mohammad Reza and Bazghandi, Atefeh and Hassanpour, Marzieh and Faruque, Mohammad Rashed Iqbal and Bradley, D.A. * (2023) Investigation of the effect of 131I on blood parameters for thyroid cancer treatment. Radiation Physics and Chemistry, 208. ISSN 0969-806X https://doi.org/10.1016/j.radphyschem.2023.110897 10.1016/j.radphyschem.2023.110897
spellingShingle QA Mathematics
QC Physics
QP Physiology
RC Internal medicine
Khandaker, Mayeen Uddin *
Hassanpour, Mehdi
Khezripour, Saeedeh
Rezaei, Mohammad Reza
Bazghandi, Atefeh
Hassanpour, Marzieh
Faruque, Mohammad Rashed Iqbal
Bradley, D.A. *
Investigation of the effect of 131I on blood parameters for thyroid cancer treatment
title Investigation of the effect of 131I on blood parameters for thyroid cancer treatment
title_full Investigation of the effect of 131I on blood parameters for thyroid cancer treatment
title_fullStr Investigation of the effect of 131I on blood parameters for thyroid cancer treatment
title_full_unstemmed Investigation of the effect of 131I on blood parameters for thyroid cancer treatment
title_short Investigation of the effect of 131I on blood parameters for thyroid cancer treatment
title_sort investigation of the effect of 131i on blood parameters for thyroid cancer treatment
topic QA Mathematics
QC Physics
QP Physiology
RC Internal medicine
url http://eprints.sunway.edu.my/2256/
http://eprints.sunway.edu.my/2256/
http://eprints.sunway.edu.my/2256/