One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation.
A new method for the synthesis of bis(1,3,5-triazine-2,4-diamines) was developed using a one-pot multicomponent approach. The synthesis was performed using the acid-catalyzed reaction of cyanoguanidine with amines and aldehydes, followed by dehydrogenative aromatization of the dihydrotriazine interm...
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| Language: | English |
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Wiley
2022
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| Online Access: | http://eprints.sunway.edu.my/2130/ http://eprints.sunway.edu.my/2130/1/chemistryselect%202022%207%20e202203038.pdf |
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| author | Muhammad Syafiq, Sahari Tiekink, Edward R. T. * Dolzhenko, Anton V |
| author_facet | Muhammad Syafiq, Sahari Tiekink, Edward R. T. * Dolzhenko, Anton V |
| author_sort | Muhammad Syafiq, Sahari |
| building | SU Institutional Repository |
| collection | Online Access |
| description | A new method for the synthesis of bis(1,3,5-triazine-2,4-diamines) was developed using a one-pot multicomponent approach. The synthesis was performed using the acid-catalyzed reaction of cyanoguanidine with amines and aldehydes, followed by dehydrogenative aromatization of the dihydrotriazine intermediates upon heating with alkali. Two types of bis(1,3,5-triazine-2,4-diamines) were prepared using either piperazine as the bifunctional amine or terephthaldehyde as the bifunctional aldehyde thus affording products with a piperazine or p-phenylene link between two 1,3,5-triazine rings. The microwave-assisted method allows fast and convenient synthesis of diverse bis(1,3,5-triazine-2,4-diamines). |
| first_indexed | 2025-11-14T21:19:39Z |
| format | Article |
| id | sunway-2130 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:19:39Z |
| publishDate | 2022 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-21302022-11-23T03:06:30Z http://eprints.sunway.edu.my/2130/ One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. Muhammad Syafiq, Sahari Tiekink, Edward R. T. * Dolzhenko, Anton V QD Chemistry RC0254 Neoplasms. Tumors. Oncology (including Cancer) RS Pharmacy and materia medica A new method for the synthesis of bis(1,3,5-triazine-2,4-diamines) was developed using a one-pot multicomponent approach. The synthesis was performed using the acid-catalyzed reaction of cyanoguanidine with amines and aldehydes, followed by dehydrogenative aromatization of the dihydrotriazine intermediates upon heating with alkali. Two types of bis(1,3,5-triazine-2,4-diamines) were prepared using either piperazine as the bifunctional amine or terephthaldehyde as the bifunctional aldehyde thus affording products with a piperazine or p-phenylene link between two 1,3,5-triazine rings. The microwave-assisted method allows fast and convenient synthesis of diverse bis(1,3,5-triazine-2,4-diamines). Wiley 2022-11-21 Article PeerReviewed text en cc_by_nc_nd_4 http://eprints.sunway.edu.my/2130/1/chemistryselect%202022%207%20e202203038.pdf Muhammad Syafiq, Sahari and Tiekink, Edward R. T. * and Dolzhenko, Anton V (2022) One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. ChemistrySelect, 7 (44). ISSN 2365-6549 https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/slct.202203038 doi.org/10.1002/slct.202203038 |
| spellingShingle | QD Chemistry RC0254 Neoplasms. Tumors. Oncology (including Cancer) RS Pharmacy and materia medica Muhammad Syafiq, Sahari Tiekink, Edward R. T. * Dolzhenko, Anton V One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. |
| title | One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. |
| title_full | One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. |
| title_fullStr | One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. |
| title_full_unstemmed | One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. |
| title_short | One-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. |
| title_sort | one-pot multicomponent synthesis of bis(diamino-1,3,5-triazines) under microwave irradiation. |
| topic | QD Chemistry RC0254 Neoplasms. Tumors. Oncology (including Cancer) RS Pharmacy and materia medica |
| url | http://eprints.sunway.edu.my/2130/ http://eprints.sunway.edu.my/2130/ http://eprints.sunway.edu.my/2130/ http://eprints.sunway.edu.my/2130/1/chemistryselect%202022%207%20e202203038.pdf |