Functional insights into Silymarin as an antiviral agent against Enterovirus A71 (EV-A71)
Enterovirus A71 (EV-A71) is a major neurovirulent agent capable of causing severe hand, foot and mouth disease (HFMD) associated with neurological complications and death. Currently, no FDA-approved antiviral is available for the treatment of EV-A71 infections. The flavonoid silymarin was shown to e...
| Main Authors: | Lalani, S.*, Masomian, Malihe *, Poh, Chit Laa * |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI
2021
|
| Subjects: | |
| Online Access: | http://eprints.sunway.edu.my/1836/ http://eprints.sunway.edu.my/1836/1/Malihe%20Masomian%20Functional%20insights%20into%20silymarin%20as%20an%20antiviral%20agent-ijms-22-08757%20%281%29.pdf |
Similar Items
Flavonoids as antiviral agents for Enterovirus A71 (EV-A71)
by: Lalani, S.*, et al.
Published: (2020)
by: Lalani, S.*, et al.
Published: (2020)
Antiviral activity of silymarin in comparison with baicalein against EV-A71
by: Lalani, S.*, et al.
Published: (2020)
by: Lalani, S.*, et al.
Published: (2020)
Molecular docking of SP40 peptide towards cellular
receptors for enterovirus 71 (EV-A71)
by: Masomian, Malihe *, et al.
Published: (2021)
by: Masomian, Malihe *, et al.
Published: (2021)
Development of novel miRNA-based vaccines and antivirals against Enterovirus 71
by: Yee, Isabel Pin Tsin *, et al.
Published: (2016)
by: Yee, Isabel Pin Tsin *, et al.
Published: (2016)
Development of novel vaccines against Enterovirus-71
by: Yee, Isabel Pin Tsin *, et al.
Published: (2015)
by: Yee, Isabel Pin Tsin *, et al.
Published: (2015)
Insights into innate and adaptive immune responses in vaccine development against EV-A71
by: Lim, Hui Xuan *, et al.
Published: (2019)
by: Lim, Hui Xuan *, et al.
Published: (2019)
Characterization of plaque variants and the involvement of Quasi-Species in a population of EV-A71
by: Mandary, M. B. *, et al.
Published: (2020)
by: Mandary, M. B. *, et al.
Published: (2020)
Impact of genetic changes in the Enterovirus 71 genome on virulence
by: Poh, Chit Laa *, et al.
Published: (2019)
by: Poh, Chit Laa *, et al.
Published: (2019)
T Cell immunity to enterovirus 71 infection in humans and implications for vaccine development
by: Yee, Isabel Pin Tsin *, et al.
Published: (2018)
by: Yee, Isabel Pin Tsin *, et al.
Published: (2018)
Impact of genetic changes, pathogenicity and antigenicity on Enterovirus- A71 vaccine development
by: Yee, Isabel Pin Tsin *, et al.
Published: (2017)
by: Yee, Isabel Pin Tsin *, et al.
Published: (2017)
Molecular mechanism of L-SP40 peptide and in vivo efficacy against EV-A71 in neonatal mice
by: Lalani, Salima, et al.
Published: (2021)
by: Lalani, Salima, et al.
Published: (2021)
Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice
by: Yee, Isabel Pin Tsin *, et al.
Published: (2019)
by: Yee, Isabel Pin Tsin *, et al.
Published: (2019)
Development of antivirals and vaccines against enterovirus 71 (EV-A71)
by: Poh, Chit Laa *
Published: (2018)
by: Poh, Chit Laa *
Published: (2018)
Pluripotent human embryonic stem cell derived neural lineages for in vitro modelling of enterovirus 71 infection and therapy
by: Yap, May Shin *, et al.
Published: (2016)
by: Yap, May Shin *, et al.
Published: (2016)
A decade of sustained selection pressure on two surface sites of the VP1 protein of Enterovirus A71 suggests that immune evasion may be an indirect driver for virulence
by: Roberts, Ryan, et al.
Published: (2019)
by: Roberts, Ryan, et al.
Published: (2019)
Structure-based design of antivirals against Envelope Glycoprotein of dengue virus
by: Anasir, M. I. *, et al.
Published: (2020)
by: Anasir, M. I. *, et al.
Published: (2020)
High-titred neutralizing antibodies to human enterovirus 71 preferentially bind to the N-terminal portion of the capsid protein VP1
by: Tan, Cheng Siang, et al.
Published: (2007)
by: Tan, Cheng Siang, et al.
Published: (2007)
Inhibition of Enterovirus 71 (EV-71 infections by a novel
antiviral peptide derived from EV-71 capsid protein VP1
by: Tan, Chee Wah, et al.
Published: (2012)
by: Tan, Chee Wah, et al.
Published: (2012)
Clinical features, diagnosis, and management of enterovirus 71
by: Ooi, Mong How, et al.
Published: (2010)
by: Ooi, Mong How, et al.
Published: (2010)
Virology, epidemiology, pathogenesis, and control of enterovirus 71.
by: Solomon, Tom, et al.
Published: (2010)
by: Solomon, Tom, et al.
Published: (2010)
Role of microRNAs in antiviral responses to dengue infection
by: Wong, Rui Rui, et al.
Published: (2020)
by: Wong, Rui Rui, et al.
Published: (2020)
RSAD2 and AIM2 modulateCV-A16 and EV-A71 replication in neuronal cells in different ways that may be associated with their 5′ non-translated regions
by: David, Perera
Published: (2017)
by: David, Perera
Published: (2017)
Development of next generation Streptococcus pneumoniae vaccines conferring broad protection
by: Masomian, Malihe *, et al.
Published: (2020)
by: Masomian, Malihe *, et al.
Published: (2020)
Recent advances in delivery of veterinary DNA vaccines against avian pathogens
by: Jazayeri, S. D. *, et al.
Published: (2019)
by: Jazayeri, S. D. *, et al.
Published: (2019)
Peptides as therapeutic agents for dengue virus
by: Chew, Miaw Fang *, et al.
Published: (2017)
by: Chew, Miaw Fang *, et al.
Published: (2017)
In vitro evaluation of the antiviral activity of heparan sulfate mimetic compounds against Enterovirus 71
by: Pourianfar, Hamid Reza, et al.
Published: (2012)
by: Pourianfar, Hamid Reza, et al.
Published: (2012)
Advances in Antigenic Peptide-Based Vaccine and Neutralizing Antibodies against Viruses Causing Hand, Foot, and Mouth Disease
by: Mohd Ishtiaq Anasir, *, et al.
Published: (2019)
by: Mohd Ishtiaq Anasir, *, et al.
Published: (2019)
Formaldehyde-Inactivated Whole-Virus Vaccine Protects a Murine Model of Enterovirus 71 Encephalomyelitis against Disease
by: Ong, Kien Chai, et al.
Published: (2010)
by: Ong, Kien Chai, et al.
Published: (2010)
Novel Multiplex Oligonucleotide-Conjugated Bead Suspension Array for Rapid Identification of Enterovirus 71 Subgenogroups
by: Wu, Y., et al.
Published: (2011)
by: Wu, Y., et al.
Published: (2011)
A generic assay for whole-genome amplification and deep sequencing of enterovirus A71
by: Tan, Le Van, et al.
Published: (2015)
by: Tan, Le Van, et al.
Published: (2015)
Nano and microparticles as potential oral vaccine carriers and adjuvants against infectious diseases
by: Jazayeri, S. D. *, et al.
Published: (2021)
by: Jazayeri, S. D. *, et al.
Published: (2021)
The conserved molecular determinants of virulence in
dengue virus
by: Zuleeza A,, et al.
Published: (2019)
by: Zuleeza A,, et al.
Published: (2019)
Development of universal influenza vaccines targeting conserved viral proteins
by: Jazayeri, S. D. *, et al.
Published: (2019)
by: Jazayeri, S. D. *, et al.
Published: (2019)
Structural vaccinology for viral vaccine design
by: Mohd Ishtiaq Anasir, *, et al.
Published: (2019)
by: Mohd Ishtiaq Anasir, *, et al.
Published: (2019)
Development of a multiplex polymerase chain reaction assay for simultaneous identification of human enterovirus 71 and coxsackievirus A16.
by: Thao, Nguyen Thi Thanh, et al.
Published: (2010)
by: Thao, Nguyen Thi Thanh, et al.
Published: (2010)
Identification and selection of immunodominant B and T cell epitopes for dengue multi-epitope-based vaccine
by: Lim, Hui Xuan *, et al.
Published: (2021)
by: Lim, Hui Xuan *, et al.
Published: (2021)
Understanding the differentiation, expansion, recruitment and suppressive activities of myeloid-derived suppressor cells in cancers
by: Lim, Hui Xuan *, et al.
Published: (2020)
by: Lim, Hui Xuan *, et al.
Published: (2020)
Enhancement of tetravalent immune responses to highly conserved epitopes of a dengue peptide vaccine conjugated to polystyrene nanoparticles
by: Chan, Yanqi, et al.
Published: (2020)
by: Chan, Yanqi, et al.
Published: (2020)
Enterovirus 71 encephalomyelitis and Japanese encephalitis can be distinguished by topographic distribution of inflammation and specific intraneuronal detection of viral antigen and RNA
by: Wong, K.T., et al.
Published: (2012)
by: Wong, K.T., et al.
Published: (2012)
Development of multi-epitope peptide-based vaccines against SARS-CoV-2
by: Lim, Hui Xuan *, et al.
Published: (2020)
by: Lim, Hui Xuan *, et al.
Published: (2020)
Similar Items
-
Flavonoids as antiviral agents for Enterovirus A71 (EV-A71)
by: Lalani, S.*, et al.
Published: (2020) -
Antiviral activity of silymarin in comparison with baicalein against EV-A71
by: Lalani, S.*, et al.
Published: (2020) -
Molecular docking of SP40 peptide towards cellular
receptors for enterovirus 71 (EV-A71)
by: Masomian, Malihe *, et al.
Published: (2021) -
Development of novel miRNA-based vaccines and antivirals against Enterovirus 71
by: Yee, Isabel Pin Tsin *, et al.
Published: (2016) -
Development of novel vaccines against Enterovirus-71
by: Yee, Isabel Pin Tsin *, et al.
Published: (2015)