Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update
With cancer remaining as one of the main causes of deaths worldwide, many studies are undergoing the effort to look for a novel and potent anticancer drug. Nanoparticles (NPs) are one of the rising fields in research for anticancer drug development. One of the key advantages of using NPs for cancer...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI
2021
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| Online Access: | http://eprints.sunway.edu.my/1763/ http://eprints.sunway.edu.my/1763/1/Teow%20Sin%20Yeang%20Development%20of%20polymer%20assisted.pdf |
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| author | Bibi Noorheen, H. M. N. Ooi, L. T. Shameli, Kamyar Nuraina, A. D. Jahid, M. M. I. Pushpamalar, Janarthanan Teow, Sin Yeang * |
| author_facet | Bibi Noorheen, H. M. N. Ooi, L. T. Shameli, Kamyar Nuraina, A. D. Jahid, M. M. I. Pushpamalar, Janarthanan Teow, Sin Yeang * |
| author_sort | Bibi Noorheen, H. M. N. |
| building | SU Institutional Repository |
| collection | Online Access |
| description | With cancer remaining as one of the main causes of deaths worldwide, many studies are undergoing the effort to look for a novel and potent anticancer drug. Nanoparticles (NPs) are one of the rising fields in research for anticancer drug development. One of the key advantages of using
NPs for cancer therapy is its high flexibility for modification, hence additional properties can be added to the NPs in order to improve its anticancer action. Polymer has attracted considerable attention to be used as a material to enhance the bioactivity of the NPs. Nanogels, which are NPs cross-linked with hydrophilic polymer network have also exhibited benefits in anticancer application.
The characteristics of these nanomaterials include non-toxic, environment-friendly, and variable physiochemical properties. Some other unique properties of polymers are also attributed by diverse methods of polymer synthesis. This then contributes to the unique properties of the nanodrugs.
This review article provides an in-depth update on the development of polymer-assisted NPs and
nanogels for cancer therapy. Topics such as the synthesis, usage, and properties of the nanomaterials
are discussed along with their mechanisms and functions in anticancer application. The advantages
and limitations are also discussed in this article. |
| first_indexed | 2025-11-14T21:18:26Z |
| format | Article |
| id | sunway-1763 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:18:26Z |
| publishDate | 2021 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-17632021-05-24T06:33:07Z http://eprints.sunway.edu.my/1763/ Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update Bibi Noorheen, H. M. N. Ooi, L. T. Shameli, Kamyar Nuraina, A. D. Jahid, M. M. I. Pushpamalar, Janarthanan Teow, Sin Yeang * RC0254 Neoplasms. Tumors. Oncology (including Cancer) With cancer remaining as one of the main causes of deaths worldwide, many studies are undergoing the effort to look for a novel and potent anticancer drug. Nanoparticles (NPs) are one of the rising fields in research for anticancer drug development. One of the key advantages of using NPs for cancer therapy is its high flexibility for modification, hence additional properties can be added to the NPs in order to improve its anticancer action. Polymer has attracted considerable attention to be used as a material to enhance the bioactivity of the NPs. Nanogels, which are NPs cross-linked with hydrophilic polymer network have also exhibited benefits in anticancer application. The characteristics of these nanomaterials include non-toxic, environment-friendly, and variable physiochemical properties. Some other unique properties of polymers are also attributed by diverse methods of polymer synthesis. This then contributes to the unique properties of the nanodrugs. This review article provides an in-depth update on the development of polymer-assisted NPs and nanogels for cancer therapy. Topics such as the synthesis, usage, and properties of the nanomaterials are discussed along with their mechanisms and functions in anticancer application. The advantages and limitations are also discussed in this article. MDPI 2021-05 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/1763/1/Teow%20Sin%20Yeang%20Development%20of%20polymer%20assisted.pdf Bibi Noorheen, H. M. N. and Ooi, L. T. and Shameli, Kamyar and Nuraina, A. D. and Jahid, M. M. I. and Pushpamalar, Janarthanan and Teow, Sin Yeang * (2021) Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update. Gels, 7 (2). p. 60. ISSN 2310-2861 http://doi.org/10.3390/gels7020060 doi:10.3390/gels7020060 |
| spellingShingle | RC0254 Neoplasms. Tumors. Oncology (including Cancer) Bibi Noorheen, H. M. N. Ooi, L. T. Shameli, Kamyar Nuraina, A. D. Jahid, M. M. I. Pushpamalar, Janarthanan Teow, Sin Yeang * Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update |
| title | Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update |
| title_full | Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update |
| title_fullStr | Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update |
| title_full_unstemmed | Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update |
| title_short | Development of polymer-assisted nanoparticles and nanogels for cancer therapy: An update |
| title_sort | development of polymer-assisted nanoparticles and nanogels for cancer therapy: an update |
| topic | RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| url | http://eprints.sunway.edu.my/1763/ http://eprints.sunway.edu.my/1763/ http://eprints.sunway.edu.my/1763/ http://eprints.sunway.edu.my/1763/1/Teow%20Sin%20Yeang%20Development%20of%20polymer%20assisted.pdf |