Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography
Highly crystalline titanium dioxide nanoparticles (TiO2 -NPs) are synthesized via a simple hydrothermal technique. After structural and compositional analysis, the as-synthesized unmodified TiO2 -NPs are tested for improvement in two modes of kilovoltage radiation therapy and singlephoton emission...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI
2021
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| Online Access: | http://eprints.sunway.edu.my/1668/ http://eprints.sunway.edu.my/1668/1/Mayeen%20Unmodified%20Titanium.pdf |
| _version_ | 1848802109304078336 |
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| author | Khalid, A. Ahmad, P. Alharthi, A. I. Muhammad, S. Khandaker, Mayeen Uddin * Faruque, M. R. I. Din, I. U. Alotaibi, M. A. |
| author_facet | Khalid, A. Ahmad, P. Alharthi, A. I. Muhammad, S. Khandaker, Mayeen Uddin * Faruque, M. R. I. Din, I. U. Alotaibi, M. A. |
| author_sort | Khalid, A. |
| building | SU Institutional Repository |
| collection | Online Access |
| description | Highly crystalline titanium dioxide nanoparticles (TiO2
-NPs) are synthesized via a simple hydrothermal technique. After structural and compositional analysis, the as-synthesized unmodified TiO2 -NPs are tested for improvement in two modes of kilovoltage radiation therapy and singlephoton emission computed tomography (SPECT)/computed tomography (CT). Our results show that the unmodified TiO2
-NPs provide an observable enhancement in CT scan image contrast ranging from 0 ± 3 HU (without NPs) to 283.7 ± 3 HU (0.23 g/mL). TiO2 -NPs has excellent biocompatibility,
selective uptake at target sites, and reduced toxicity. The unmodified TiO2 -NPs as a contrast agent can significantly improve the existing methods of diagnosing and treating cancer. |
| first_indexed | 2025-11-14T21:18:07Z |
| format | Article |
| id | sunway-1668 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:18:07Z |
| publishDate | 2021 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-16682021-04-19T03:59:38Z http://eprints.sunway.edu.my/1668/ Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography Khalid, A. Ahmad, P. Alharthi, A. I. Muhammad, S. Khandaker, Mayeen Uddin * Faruque, M. R. I. Din, I. U. Alotaibi, M. A. R895-920 Medical Physics/Medical Radiology Highly crystalline titanium dioxide nanoparticles (TiO2 -NPs) are synthesized via a simple hydrothermal technique. After structural and compositional analysis, the as-synthesized unmodified TiO2 -NPs are tested for improvement in two modes of kilovoltage radiation therapy and singlephoton emission computed tomography (SPECT)/computed tomography (CT). Our results show that the unmodified TiO2 -NPs provide an observable enhancement in CT scan image contrast ranging from 0 ± 3 HU (without NPs) to 283.7 ± 3 HU (0.23 g/mL). TiO2 -NPs has excellent biocompatibility, selective uptake at target sites, and reduced toxicity. The unmodified TiO2 -NPs as a contrast agent can significantly improve the existing methods of diagnosing and treating cancer. MDPI 2021 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/1668/1/Mayeen%20Unmodified%20Titanium.pdf Khalid, A. and Ahmad, P. and Alharthi, A. I. and Muhammad, S. and Khandaker, Mayeen Uddin * and Faruque, M. R. I. and Din, I. U. and Alotaibi, M. A. (2021) Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography. Crystals, 11 (2). p. 171. ISSN 2073-4352 http://doi.org/10.3390/cryst11020171 doi:10.3390/cryst11020171 |
| spellingShingle | R895-920 Medical Physics/Medical Radiology Khalid, A. Ahmad, P. Alharthi, A. I. Muhammad, S. Khandaker, Mayeen Uddin * Faruque, M. R. I. Din, I. U. Alotaibi, M. A. Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
| title | Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
| title_full | Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
| title_fullStr | Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
| title_full_unstemmed | Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
| title_short | Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
| title_sort | unmodified titanium dioxide nanoparticles as a potential contrast agent in photon emission computed tomography |
| topic | R895-920 Medical Physics/Medical Radiology |
| url | http://eprints.sunway.edu.my/1668/ http://eprints.sunway.edu.my/1668/ http://eprints.sunway.edu.my/1668/ http://eprints.sunway.edu.my/1668/1/Mayeen%20Unmodified%20Titanium.pdf |