Tailored Ge-doped fibres for passive electron radiotherapy dosimetry

Study has been made of the thermoluminescence yield of various novel tailor-made silica fibres, 6 and 8 mol % Ge-doped, with four differing outer dimensions, comprised of flat and cylindrical shapes, subjected to electron irradiation. Main thermoluminescence dosimetric characteristics have been inv...

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Main Authors: Siti Nurasiah, M. N, Abdul Sani, S.F., Khandaker, Mayeen Uddin *, Ung, N.M., Almugren, K.S., Alkallas, F.H., Bradley, D.A. *
Format: Article
Language:English
Published: Public Library of Science 2020
Subjects:
Online Access:http://eprints.sunway.edu.my/1663/
http://eprints.sunway.edu.my/1663/1/Mayeen%20Tailored%20Ge%20doped.pdf
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author Siti Nurasiah, M. N
Abdul Sani, S.F.
Khandaker, Mayeen Uddin *
Ung, N.M.
Almugren, K.S.
Alkallas, F.H.
Bradley, D.A. *
author_facet Siti Nurasiah, M. N
Abdul Sani, S.F.
Khandaker, Mayeen Uddin *
Ung, N.M.
Almugren, K.S.
Alkallas, F.H.
Bradley, D.A. *
author_sort Siti Nurasiah, M. N
building SU Institutional Repository
collection Online Access
description Study has been made of the thermoluminescence yield of various novel tailor-made silica fibres, 6 and 8 mol % Ge-doped, with four differing outer dimensions, comprised of flat and cylindrical shapes, subjected to electron irradiation. Main thermoluminescence dosimetric characteristics have been investigated, including the glow curve, dose response, energy dependence, minimum detectable dose, effective atomic number, linearity of index and sensitivity of the fibres. The studies have also established the uncertainties involved as well as the stability of response in terms of fading effect, reproducibility and annealing. In addition, dose-rate dependence was accounted for as this has the potential to be a significant factor in radiotherapy applications. The 6 and 8 mol % fibres have been found to provide highly linear dose response within the range 1 to 4 Gy, the smallest size flat fibre, 6 mol% Ge-doped, showing the greatest response by a factor of 1.1 with respect to the highly popular LiF phosphor-based medium TLD100. All of the fibres also showed excellent reproducibility with a standard deviation of < 2% and < 4% for 6 and 8 mol % Ge-doped fibres respectively. For fading evaluation, the smallest 6 mol% Ge-doped dimension flat fibre, i.e., 85 × 270 μm displayed the lowest signal loss within 120 days post-irradiation, at around 26.9% also showing a response superior to that of all of the other fibres. Moreover, all the fibres and TLD-100 chips showed independence with respect to electron irradiation energy and dose-rate. Compared with the 8 mol% Ge-doped optical fibres, the 6 mol% Ge-doped flat optical fibres have been demonstrated to possess more desirable performance features for passive dosimetry, serving as a suitable alternative to TLD-100 for medical irradiation treatment applications.
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spelling sunway-16632021-03-25T05:05:26Z http://eprints.sunway.edu.my/1663/ Tailored Ge-doped fibres for passive electron radiotherapy dosimetry Siti Nurasiah, M. N Abdul Sani, S.F. Khandaker, Mayeen Uddin * Ung, N.M. Almugren, K.S. Alkallas, F.H. Bradley, D.A. * R895-920 Medical Physics/Medical Radiology Study has been made of the thermoluminescence yield of various novel tailor-made silica fibres, 6 and 8 mol % Ge-doped, with four differing outer dimensions, comprised of flat and cylindrical shapes, subjected to electron irradiation. Main thermoluminescence dosimetric characteristics have been investigated, including the glow curve, dose response, energy dependence, minimum detectable dose, effective atomic number, linearity of index and sensitivity of the fibres. The studies have also established the uncertainties involved as well as the stability of response in terms of fading effect, reproducibility and annealing. In addition, dose-rate dependence was accounted for as this has the potential to be a significant factor in radiotherapy applications. The 6 and 8 mol % fibres have been found to provide highly linear dose response within the range 1 to 4 Gy, the smallest size flat fibre, 6 mol% Ge-doped, showing the greatest response by a factor of 1.1 with respect to the highly popular LiF phosphor-based medium TLD100. All of the fibres also showed excellent reproducibility with a standard deviation of < 2% and < 4% for 6 and 8 mol % Ge-doped fibres respectively. For fading evaluation, the smallest 6 mol% Ge-doped dimension flat fibre, i.e., 85 × 270 μm displayed the lowest signal loss within 120 days post-irradiation, at around 26.9% also showing a response superior to that of all of the other fibres. Moreover, all the fibres and TLD-100 chips showed independence with respect to electron irradiation energy and dose-rate. Compared with the 8 mol% Ge-doped optical fibres, the 6 mol% Ge-doped flat optical fibres have been demonstrated to possess more desirable performance features for passive dosimetry, serving as a suitable alternative to TLD-100 for medical irradiation treatment applications. Public Library of Science 2020-07 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/1663/1/Mayeen%20Tailored%20Ge%20doped.pdf Siti Nurasiah, M. N and Abdul Sani, S.F. and Khandaker, Mayeen Uddin * and Ung, N.M. and Almugren, K.S. and Alkallas, F.H. and Bradley, D.A. * (2020) Tailored Ge-doped fibres for passive electron radiotherapy dosimetry. PLOS ONE, 15 (7). e0235053. ISSN 1932-6203 http://doi.org/10.1371/journal.pone.0235053 doi:10.1371/journal.pone.0235053
spellingShingle R895-920 Medical Physics/Medical Radiology
Siti Nurasiah, M. N
Abdul Sani, S.F.
Khandaker, Mayeen Uddin *
Ung, N.M.
Almugren, K.S.
Alkallas, F.H.
Bradley, D.A. *
Tailored Ge-doped fibres for passive electron radiotherapy dosimetry
title Tailored Ge-doped fibres for passive electron radiotherapy dosimetry
title_full Tailored Ge-doped fibres for passive electron radiotherapy dosimetry
title_fullStr Tailored Ge-doped fibres for passive electron radiotherapy dosimetry
title_full_unstemmed Tailored Ge-doped fibres for passive electron radiotherapy dosimetry
title_short Tailored Ge-doped fibres for passive electron radiotherapy dosimetry
title_sort tailored ge-doped fibres for passive electron radiotherapy dosimetry
topic R895-920 Medical Physics/Medical Radiology
url http://eprints.sunway.edu.my/1663/
http://eprints.sunway.edu.my/1663/
http://eprints.sunway.edu.my/1663/
http://eprints.sunway.edu.my/1663/1/Mayeen%20Tailored%20Ge%20doped.pdf