Synthesis, structural characterisation and theoretical studies of a novel pyridazine derivative: Investigations of anti-inflammatory activity and inhibition of α-glucosidase
X-ray crystallography on pyridazine 1 (ethyl 2-(3-methyl-4-(4-methylbenzyl)-6-oxopyridazin1(6H)-yl)acetate) shows the planar pyridazinyl ring to exhibit significant delocalisation of πelectron density over the constituent atoms and to be substituted with oxo, methyl, (4- methylphenyl)methyl and N-b...
| Main Authors: | Zaoui, Younes, Ramli, Youssef, Tan, Sang Loon *, Tiekink, Edward R. T. *, Chemlal, L., Mague, Joel T., Taoufik, Jamal, Faouzi, M. E. A., Ansar, M'hammed |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021
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| Subjects: | |
| Online Access: | http://eprints.sunway.edu.my/1652/ http://eprints.sunway.edu.my/1652/1/Tiekink%20Synthesis%20structural_accepted.pdf |
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