Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications

Gold nanoparticles (AuNPs) are extensively studied nanoparticles (NPs) and are known to have profound applications in medicine. There are various methods to synthesize AuNPs which are generally categorized into two main types: chemical and physical synthesis. Continuous efforts have been devoted to...

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Main Authors: Lee, Kar Xin, Shameli, Kamyar, Yew, Yen Pin, Teow, Sin Yeang *, Jahangirian, Hossein, Rafiee-Moghaddam, Roshanak, Webster, Thomas
Format: Article
Language:English
Published: Dove Medical Press 2020
Subjects:
Online Access:http://eprints.sunway.edu.my/1562/
http://eprints.sunway.edu.my/1562/1/Teow%20Sin%20Yeang%20Recent%20developments%20in%20the%20facile%20bio-synthesis%20of%20gold%20nanoparticles%20%28AuNPs%29%20and%20their%20biomedical%20applications.pdf
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author Lee, Kar Xin
Shameli, Kamyar
Yew, Yen Pin
Teow, Sin Yeang *
Jahangirian, Hossein
Rafiee-Moghaddam, Roshanak
Webster, Thomas
author_facet Lee, Kar Xin
Shameli, Kamyar
Yew, Yen Pin
Teow, Sin Yeang *
Jahangirian, Hossein
Rafiee-Moghaddam, Roshanak
Webster, Thomas
author_sort Lee, Kar Xin
building SU Institutional Repository
collection Online Access
description Gold nanoparticles (AuNPs) are extensively studied nanoparticles (NPs) and are known to have profound applications in medicine. There are various methods to synthesize AuNPs which are generally categorized into two main types: chemical and physical synthesis. Continuous efforts have been devoted to search for other more environmental-friendly and economical large-scale methods, such as environmentally friendly biological methods known as green synthesis. Green synthesis is especially important to minimize the harmful chemical and toxic by-products during the conventional synthesis of AuNPs. Green materials such as plants, fungi, microorganisms, enzymes and biopolymers are currently used to synthesize various NPs. Biosynthesized AuNPs are generally safer for use in biomedical applications since they come from natural materials themselves. Multiple surface functionalities of AuNPs allow them to be more robust and flexible when combined with different biological assemblies or modifications for enhanced applications. This review focuses on recent developments of green synthesized AuNPs and discusses their numerous biomedical applications. Sources of green materials with successful examples and other key parameters that determine the functionalities of AuNPs are also discussed in this review.
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language English
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publishDate 2020
publisher Dove Medical Press
recordtype eprints
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spelling sunway-15622021-01-27T02:22:53Z http://eprints.sunway.edu.my/1562/ Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications Lee, Kar Xin Shameli, Kamyar Yew, Yen Pin Teow, Sin Yeang * Jahangirian, Hossein Rafiee-Moghaddam, Roshanak Webster, Thomas QH301 Biology R Medicine (General) Gold nanoparticles (AuNPs) are extensively studied nanoparticles (NPs) and are known to have profound applications in medicine. There are various methods to synthesize AuNPs which are generally categorized into two main types: chemical and physical synthesis. Continuous efforts have been devoted to search for other more environmental-friendly and economical large-scale methods, such as environmentally friendly biological methods known as green synthesis. Green synthesis is especially important to minimize the harmful chemical and toxic by-products during the conventional synthesis of AuNPs. Green materials such as plants, fungi, microorganisms, enzymes and biopolymers are currently used to synthesize various NPs. Biosynthesized AuNPs are generally safer for use in biomedical applications since they come from natural materials themselves. Multiple surface functionalities of AuNPs allow them to be more robust and flexible when combined with different biological assemblies or modifications for enhanced applications. This review focuses on recent developments of green synthesized AuNPs and discusses their numerous biomedical applications. Sources of green materials with successful examples and other key parameters that determine the functionalities of AuNPs are also discussed in this review. Dove Medical Press 2020-01-16 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/1562/1/Teow%20Sin%20Yeang%20Recent%20developments%20in%20the%20facile%20bio-synthesis%20of%20gold%20nanoparticles%20%28AuNPs%29%20and%20their%20biomedical%20applications.pdf Lee, Kar Xin and Shameli, Kamyar and Yew, Yen Pin and Teow, Sin Yeang * and Jahangirian, Hossein and Rafiee-Moghaddam, Roshanak and Webster, Thomas (2020) Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications. International Journal of Nanomedicine, 15. pp. 275-300. ISSN 1178-2013 http://doi.org/10.2147/IJN.S233789 doi:10.2147/IJN.S233789
spellingShingle QH301 Biology
R Medicine (General)
Lee, Kar Xin
Shameli, Kamyar
Yew, Yen Pin
Teow, Sin Yeang *
Jahangirian, Hossein
Rafiee-Moghaddam, Roshanak
Webster, Thomas
Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications
title Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications
title_full Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications
title_fullStr Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications
title_full_unstemmed Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications
title_short Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications
title_sort recent developments in the facile bio-synthesis of gold nanoparticles (aunps) and their biomedical applications
topic QH301 Biology
R Medicine (General)
url http://eprints.sunway.edu.my/1562/
http://eprints.sunway.edu.my/1562/
http://eprints.sunway.edu.my/1562/
http://eprints.sunway.edu.my/1562/1/Teow%20Sin%20Yeang%20Recent%20developments%20in%20the%20facile%20bio-synthesis%20of%20gold%20nanoparticles%20%28AuNPs%29%20and%20their%20biomedical%20applications.pdf