Flavonoids as antiviral agents for Enterovirus A71 (EV-A71)
Flavonoids are natural biomolecules that are known to be effective antivirals. These biomolecules can act at different stages of viral infection, particularly at the molecular level to inhibit viral growth. Enterovirus A71 (EV-A71), a non-enveloped RNA virus, is one of the causative agents of hand,...
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| Format: | Article |
| Language: | English |
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MDPI
2020
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| Online Access: | http://eprints.sunway.edu.my/1215/ http://eprints.sunway.edu.my/1215/1/Poh%20Chit%20Lah%20Flavonoids%20as%20antiviral%20agents.pdf |
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| author | Lalani, S.* Poh, Chit Laa * |
| author_facet | Lalani, S.* Poh, Chit Laa * |
| author_sort | Lalani, S.* |
| building | SU Institutional Repository |
| collection | Online Access |
| description | Flavonoids are natural biomolecules that are known to be effective antivirals. These biomolecules can act at different stages of viral infection, particularly at the molecular level to inhibit viral growth. Enterovirus A71 (EV-A71), a non-enveloped RNA virus, is one of the causative agents of hand, foot and mouth disease (HFMD), which is prevalent in Asia. Despite much effort, no clinically
approved antiviral treatment is available for children suffering from HFMD. Flavonoids from plants serve as a vast reservoir of therapeutically active constituents that have been explored as potential antiviral candidates against RNA and DNA viruses. Here, we reviewed flavonoids as evidence-based natural sources of antivirals against non-picornaviruses and picornaviruses. |
| first_indexed | 2025-11-14T21:16:23Z |
| format | Article |
| id | sunway-1215 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:16:23Z |
| publishDate | 2020 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-12152020-10-01T09:29:29Z http://eprints.sunway.edu.my/1215/ Flavonoids as antiviral agents for Enterovirus A71 (EV-A71) Lalani, S.* Poh, Chit Laa * QR355 Virology Flavonoids are natural biomolecules that are known to be effective antivirals. These biomolecules can act at different stages of viral infection, particularly at the molecular level to inhibit viral growth. Enterovirus A71 (EV-A71), a non-enveloped RNA virus, is one of the causative agents of hand, foot and mouth disease (HFMD), which is prevalent in Asia. Despite much effort, no clinically approved antiviral treatment is available for children suffering from HFMD. Flavonoids from plants serve as a vast reservoir of therapeutically active constituents that have been explored as potential antiviral candidates against RNA and DNA viruses. Here, we reviewed flavonoids as evidence-based natural sources of antivirals against non-picornaviruses and picornaviruses. MDPI 2020-02-06 Article PeerReviewed text en cc_by_nc_nd_4 http://eprints.sunway.edu.my/1215/1/Poh%20Chit%20Lah%20Flavonoids%20as%20antiviral%20agents.pdf Lalani, S.* and Poh, Chit Laa * (2020) Flavonoids as antiviral agents for Enterovirus A71 (EV-A71). Viruses, 12 (2). p. 184. ISSN 1999-4915 http://doi.org/10.3390/v12020184 doi:10.3390/v12020184 |
| spellingShingle | QR355 Virology Lalani, S.* Poh, Chit Laa * Flavonoids as antiviral agents for Enterovirus A71 (EV-A71) |
| title | Flavonoids as antiviral agents for Enterovirus A71 (EV-A71) |
| title_full | Flavonoids as antiviral agents for Enterovirus A71 (EV-A71) |
| title_fullStr | Flavonoids as antiviral agents for Enterovirus A71 (EV-A71) |
| title_full_unstemmed | Flavonoids as antiviral agents for Enterovirus A71 (EV-A71) |
| title_short | Flavonoids as antiviral agents for Enterovirus A71 (EV-A71) |
| title_sort | flavonoids as antiviral agents for enterovirus a71 (ev-a71) |
| topic | QR355 Virology |
| url | http://eprints.sunway.edu.my/1215/ http://eprints.sunway.edu.my/1215/ http://eprints.sunway.edu.my/1215/ http://eprints.sunway.edu.my/1215/1/Poh%20Chit%20Lah%20Flavonoids%20as%20antiviral%20agents.pdf |