Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus
Drug resistance developed in human pathogenic bacteria is emerging and has become a global problem. Methicillin-resistant Staphylococcus aureus (MRSA) spreading in both hospital and community areas has posed a great impact to global public health. Current antibiotics used against these resistant str...
| Main Authors: | , , |
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| Format: | Book Section |
| Language: | English |
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InTech Open
2018
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| Online Access: | http://eprints.sunway.edu.my/1146/ http://eprints.sunway.edu.my/1146/1/Teow%20Sin%20Yeang%20Non-microbial%20Natural%20Products.pdf |
| _version_ | 1848801986788458496 |
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| author | Chew, Jactty * Peh, Suat Cheng * Teow, Sin Yeang * |
| author2 | Hemeg, Hassan |
| author_facet | Hemeg, Hassan Chew, Jactty * Peh, Suat Cheng * Teow, Sin Yeang * |
| author_sort | Chew, Jactty * |
| building | SU Institutional Repository |
| collection | Online Access |
| description | Drug resistance developed in human pathogenic bacteria is emerging and has become a global problem. Methicillin-resistant Staphylococcus aureus (MRSA) spreading in both hospital and community areas has posed a great impact to global public health. Current antibiotics used against these resistant strains are no longer efficacious and the search for new alternative is in urgent need. In the past decades, natural products have demonstrated multiple biological activities in biomedical areas including their antibacterial actions against various drug-resistant bacteria. More promisingly, some natural products could reverse the resistance of bacteria to the antibiotics, making the target bacteria susceptible to these drugs again. Numerous natural products have also exhibited potent synergism against the drug-resistant bacteria when used in combination with various types of antibiotics. Recently, several antibacterials derived from microbes have been developed and approved by Food and Drug Administration (FDA) for clinical use. In this chapter, we discuss the potential use of non-microbial natural products in controlling Staphylococcus aureus (S. aureus)‘s growth, and the underlying challenges in developing the natural products into clinical applications. |
| first_indexed | 2025-11-14T21:16:10Z |
| format | Book Section |
| id | sunway-1146 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:16:10Z |
| publishDate | 2018 |
| publisher | InTech Open |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-11462019-11-27T07:40:34Z http://eprints.sunway.edu.my/1146/ Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus Chew, Jactty * Peh, Suat Cheng * Teow, Sin Yeang * RM Therapeutics. Pharmacology Drug resistance developed in human pathogenic bacteria is emerging and has become a global problem. Methicillin-resistant Staphylococcus aureus (MRSA) spreading in both hospital and community areas has posed a great impact to global public health. Current antibiotics used against these resistant strains are no longer efficacious and the search for new alternative is in urgent need. In the past decades, natural products have demonstrated multiple biological activities in biomedical areas including their antibacterial actions against various drug-resistant bacteria. More promisingly, some natural products could reverse the resistance of bacteria to the antibiotics, making the target bacteria susceptible to these drugs again. Numerous natural products have also exhibited potent synergism against the drug-resistant bacteria when used in combination with various types of antibiotics. Recently, several antibacterials derived from microbes have been developed and approved by Food and Drug Administration (FDA) for clinical use. In this chapter, we discuss the potential use of non-microbial natural products in controlling Staphylococcus aureus (S. aureus)‘s growth, and the underlying challenges in developing the natural products into clinical applications. InTech Open Hemeg, Hassan Ozbak, Hani Farhat Afrin, 2018-04-06 Book Section PeerReviewed text en cc_by_nc_nd_4 http://eprints.sunway.edu.my/1146/1/Teow%20Sin%20Yeang%20Non-microbial%20Natural%20Products.pdf Chew, Jactty * and Peh, Suat Cheng * and Teow, Sin Yeang * (2018) Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus. In: Staphylococcus Aureus. InTech Open, London,UK. ISBN 978-1-78984-593-8 http://doi.org/10.5772/intechopen.74588 doi:10.5772/intechopen.74588 |
| spellingShingle | RM Therapeutics. Pharmacology Chew, Jactty * Peh, Suat Cheng * Teow, Sin Yeang * Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus |
| title | Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus |
| title_full | Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus |
| title_fullStr | Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus |
| title_full_unstemmed | Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus |
| title_short | Non-microbial natural products that inhibit drug-resistant Staphylococcus aureus |
| title_sort | non-microbial natural products that inhibit drug-resistant staphylococcus aureus |
| topic | RM Therapeutics. Pharmacology |
| url | http://eprints.sunway.edu.my/1146/ http://eprints.sunway.edu.my/1146/ http://eprints.sunway.edu.my/1146/ http://eprints.sunway.edu.my/1146/1/Teow%20Sin%20Yeang%20Non-microbial%20Natural%20Products.pdf |