Recent advances in delivery of veterinary DNA vaccines against avian pathogens

Veterinary vaccines need to have desired characteristics, such as being effective, inexpensive, easy to administer, suitable for mass vaccination and stable under field conditions. DNA vaccines have been proposed as potential solutions for poultry diseases since they are subunit vaccines with no r...

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Main Authors: Jazayeri, S. D. *, Poh, Chit Laa *
Format: Article
Language:English
Published: BMC 2019
Subjects:
Online Access:http://eprints.sunway.edu.my/1114/
http://eprints.sunway.edu.my/1114/1/Seyed%20Davoud%20Recent%20advances%20in%20delivery%20of%20veterinary_.pdf
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author Jazayeri, S. D. *
Poh, Chit Laa *
author_facet Jazayeri, S. D. *
Poh, Chit Laa *
author_sort Jazayeri, S. D. *
building SU Institutional Repository
collection Online Access
description Veterinary vaccines need to have desired characteristics, such as being effective, inexpensive, easy to administer, suitable for mass vaccination and stable under field conditions. DNA vaccines have been proposed as potential solutions for poultry diseases since they are subunit vaccines with no risk of infection or reversion to virulence. DNA vaccines can be utilized for simultaneous immunizations against multiple pathogens and are relatively easy to design and inexpensive to manufacture and store. Administration of DNA vaccines has been shown to stimulate immune responses and provide protection from challenges in different animal models. Although DNA vaccines offer advantages, setbacks including the inability to induce strong immunity, and the fact that they are not currently applicable for mass vaccination impede the use of DNA vaccines in the poultry industry. The use of either biological or physical carriers has been proposed as a solution to overcome the current delivery limitations of DNA vaccines for veterinary applications. This review presents an overview of the recent development of carriers for delivery of veterinary DNA vaccines against avian pathogens.
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spelling sunway-11142019-10-22T09:36:40Z http://eprints.sunway.edu.my/1114/ Recent advances in delivery of veterinary DNA vaccines against avian pathogens Jazayeri, S. D. * Poh, Chit Laa * QR355 Virology Veterinary vaccines need to have desired characteristics, such as being effective, inexpensive, easy to administer, suitable for mass vaccination and stable under field conditions. DNA vaccines have been proposed as potential solutions for poultry diseases since they are subunit vaccines with no risk of infection or reversion to virulence. DNA vaccines can be utilized for simultaneous immunizations against multiple pathogens and are relatively easy to design and inexpensive to manufacture and store. Administration of DNA vaccines has been shown to stimulate immune responses and provide protection from challenges in different animal models. Although DNA vaccines offer advantages, setbacks including the inability to induce strong immunity, and the fact that they are not currently applicable for mass vaccination impede the use of DNA vaccines in the poultry industry. The use of either biological or physical carriers has been proposed as a solution to overcome the current delivery limitations of DNA vaccines for veterinary applications. This review presents an overview of the recent development of carriers for delivery of veterinary DNA vaccines against avian pathogens. BMC 2019-10-10 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/1114/1/Seyed%20Davoud%20Recent%20advances%20in%20delivery%20of%20veterinary_.pdf Jazayeri, S. D. * and Poh, Chit Laa * (2019) Recent advances in delivery of veterinary DNA vaccines against avian pathogens. Veterinary Research, 50 (78). ISSN 1297-9716 http://doi.org/10.1186/s13567-019-0698-z doi:10.1186/s13567-019-0698-z
spellingShingle QR355 Virology
Jazayeri, S. D. *
Poh, Chit Laa *
Recent advances in delivery of veterinary DNA vaccines against avian pathogens
title Recent advances in delivery of veterinary DNA vaccines against avian pathogens
title_full Recent advances in delivery of veterinary DNA vaccines against avian pathogens
title_fullStr Recent advances in delivery of veterinary DNA vaccines against avian pathogens
title_full_unstemmed Recent advances in delivery of veterinary DNA vaccines against avian pathogens
title_short Recent advances in delivery of veterinary DNA vaccines against avian pathogens
title_sort recent advances in delivery of veterinary dna vaccines against avian pathogens
topic QR355 Virology
url http://eprints.sunway.edu.my/1114/
http://eprints.sunway.edu.my/1114/
http://eprints.sunway.edu.my/1114/
http://eprints.sunway.edu.my/1114/1/Seyed%20Davoud%20Recent%20advances%20in%20delivery%20of%20veterinary_.pdf