A decade of sustained selection pressure on two surface sites of the VP1 protein of Enterovirus A71 suggests that immune evasion may be an indirect driver for virulence

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A decade of sustained selection pressure on two surface sites of the VP1 protein of Enterovirus A71 suggests that immune evasion may be an indirect driver for virulence

Enterovirus A71 (EV-A71) is an emerging pathogen in the Enterovirus A species group. EV-A71 causes hand, foot and mouth disease (HFMD), with virulent variants exhibiting polio-like acute faccid paralysis and other central nervous system manifestations. We analysed all enterovirus A71 complete genome...

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Bibliographic Details
Main Authors:	Roberts, Ryan, Yee, Isabel Pin Tsin , Mujawar, Shama , Lahiri, Chandrajit , Poh, Chit Laa , Gatherer, Derek
Format:	Article
Language:	English
Published:	Nature Research 2019
Subjects:	QR355 Virology
Online Access:	http://eprints.sunway.edu.my/1098/ http://eprints.sunway.edu.my/1098/1/Poh%20CL_A%20decade%20of%20sustained%20selection%20pressure%20on%20two.pdf

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