Structural vaccinology for viral vaccine design
Although vaccines have proven pivotal against arrays of infectious viral diseases, there are still no effective vaccines against many viruses. New structural insights into the viral envelope, protein conformation, and antigenic epitopes can guide the design of novel vaccines against challenging viru...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media
2019
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| Online Access: | http://eprints.sunway.edu.my/1097/ http://eprints.sunway.edu.my/1097/1/Poh%20CL_Structural%20Vaccinology%20for%20Viral%20Vaccine%20Design.pdf |
| _version_ | 1848801973276508160 |
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| author | Mohd Ishtiaq Anasir, * Poh, Chit Laa * |
| author_facet | Mohd Ishtiaq Anasir, * Poh, Chit Laa * |
| author_sort | Mohd Ishtiaq Anasir, * |
| building | SU Institutional Repository |
| collection | Online Access |
| description | Although vaccines have proven pivotal against arrays of infectious viral diseases, there are still no effective vaccines against many viruses. New structural insights into the viral envelope, protein conformation, and antigenic epitopes can guide the design of novel vaccines against challenging viruses such as human immunodeficiency virus (HIV), hepatitis C virus, enterovirus A71, and dengue virus. Recent studies demonstrated that
applications of this structural information can solve some of the vaccine conundrums. This review focuses on recent advances in structure-based vaccine design, or structural
vaccinology, for novel and innovative viral vaccine design. |
| first_indexed | 2025-11-14T21:15:57Z |
| format | Article |
| id | sunway-1097 |
| institution | Sunway University |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T21:15:57Z |
| publishDate | 2019 |
| publisher | Frontiers Media |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | sunway-10972019-09-19T01:59:36Z http://eprints.sunway.edu.my/1097/ Structural vaccinology for viral vaccine design Mohd Ishtiaq Anasir, * Poh, Chit Laa * QR355 Virology Although vaccines have proven pivotal against arrays of infectious viral diseases, there are still no effective vaccines against many viruses. New structural insights into the viral envelope, protein conformation, and antigenic epitopes can guide the design of novel vaccines against challenging viruses such as human immunodeficiency virus (HIV), hepatitis C virus, enterovirus A71, and dengue virus. Recent studies demonstrated that applications of this structural information can solve some of the vaccine conundrums. This review focuses on recent advances in structure-based vaccine design, or structural vaccinology, for novel and innovative viral vaccine design. Frontiers Media 2019-04-16 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/1097/1/Poh%20CL_Structural%20Vaccinology%20for%20Viral%20Vaccine%20Design.pdf Mohd Ishtiaq Anasir, * and Poh, Chit Laa * (2019) Structural vaccinology for viral vaccine design. Frontiers in Microbiology, 10. p. 738. ISSN 1664-302X http://doi.org/10.3389/fmicb.2019.00738 doi:10.3389/fmicb.2019.00738 |
| spellingShingle | QR355 Virology Mohd Ishtiaq Anasir, * Poh, Chit Laa * Structural vaccinology for viral vaccine design |
| title | Structural vaccinology for viral vaccine design |
| title_full | Structural vaccinology for viral vaccine design |
| title_fullStr | Structural vaccinology for viral vaccine design |
| title_full_unstemmed | Structural vaccinology for viral vaccine design |
| title_short | Structural vaccinology for viral vaccine design |
| title_sort | structural vaccinology for viral vaccine design |
| topic | QR355 Virology |
| url | http://eprints.sunway.edu.my/1097/ http://eprints.sunway.edu.my/1097/ http://eprints.sunway.edu.my/1097/ http://eprints.sunway.edu.my/1097/1/Poh%20CL_Structural%20Vaccinology%20for%20Viral%20Vaccine%20Design.pdf |