Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images

Abstract: Foveal avascular zone (FAZ) is the fovea devoid of capillaries in the macular region. An enlargement of FAZ is usually found in eyes with diabetic retinopathy (DR) resulting from a loss of capillaries in the perifoveal capillary network. Monitoring FAZ area enlargement at non-proliferative...

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Main Authors: Ahmad Fadzil, M Hani, Izhar, Lila Isnita, Nugroho, Hanung Adi
Format: Citation Index Journal
Language:English
Published: Inderscience Publishers 2011
Subjects:
Online Access:http://scholars.utp.edu.my/id/eprint/3181/
http://scholars.utp.edu.my/id/eprint/3181/1/IJMEI_-_Area_Analysis_of_FAZ_new1.pdf
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author Ahmad Fadzil, M Hani
Izhar, Lila Isnita
Nugroho, Hanung Adi
author_facet Ahmad Fadzil, M Hani
Izhar, Lila Isnita
Nugroho, Hanung Adi
author_sort Ahmad Fadzil, M Hani
building UTP Institutional Repository
collection Online Access
description Abstract: Foveal avascular zone (FAZ) is the fovea devoid of capillaries in the macular region. An enlargement of FAZ is usually found in eyes with diabetic retinopathy (DR) resulting from a loss of capillaries in the perifoveal capillary network. Monitoring FAZ area enlargement at non-proliferative DR (NPDR) stage enables physicians to take preventive measures to curb progression of the disease to proliferative DR (PDR) stage and visual loss. Currently it is difficult to discern the FAZ area and to measure its enlargement in an objective manner using on color fundus images instead we require performing fundus fluorescein angiogram. Fundus image analysis of FAZ presents several challenges such as high image, improper illumination, glare, fadeout, loss of focus and artifacts arising from reflection, refraction and dispersion. A new automated approach for area analysis of FAZ using color fundus images has been developed. Here, a binary map of retinal vasculature is computer generated from the color fundus image by extraction and reconstruction of retinal vasculature. The binary image is then used to determine vessel ends and pathologies surrounding FAZ for area analysis.
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institution Universiti Teknologi Petronas
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spelling oai:scholars.utp.edu.my:31812017-01-19T08:23:05Z http://scholars.utp.edu.my/id/eprint/3181/ Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images Ahmad Fadzil, M Hani Izhar, Lila Isnita Nugroho, Hanung Adi RE Ophthalmology QA75 Electronic computers. Computer science Abstract: Foveal avascular zone (FAZ) is the fovea devoid of capillaries in the macular region. An enlargement of FAZ is usually found in eyes with diabetic retinopathy (DR) resulting from a loss of capillaries in the perifoveal capillary network. Monitoring FAZ area enlargement at non-proliferative DR (NPDR) stage enables physicians to take preventive measures to curb progression of the disease to proliferative DR (PDR) stage and visual loss. Currently it is difficult to discern the FAZ area and to measure its enlargement in an objective manner using on color fundus images instead we require performing fundus fluorescein angiogram. Fundus image analysis of FAZ presents several challenges such as high image, improper illumination, glare, fadeout, loss of focus and artifacts arising from reflection, refraction and dispersion. A new automated approach for area analysis of FAZ using color fundus images has been developed. Here, a binary map of retinal vasculature is computer generated from the color fundus image by extraction and reconstruction of retinal vasculature. The binary image is then used to determine vessel ends and pathologies surrounding FAZ for area analysis. Inderscience Publishers 2011 Citation Index Journal PeerReviewed application/pdf en http://scholars.utp.edu.my/id/eprint/3181/1/IJMEI_-_Area_Analysis_of_FAZ_new1.pdf Ahmad Fadzil, M Hani and Izhar, Lila Isnita and Nugroho, Hanung Adi (2011) Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images. [Citation Index Journal]
spellingShingle RE Ophthalmology
QA75 Electronic computers. Computer science
Ahmad Fadzil, M Hani
Izhar, Lila Isnita
Nugroho, Hanung Adi
Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images
title Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images
title_full Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images
title_fullStr Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images
title_full_unstemmed Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images
title_short Area Analysis of Foveal Avascular Zone in Diabetic Retinopathy Color Fundus Images
title_sort area analysis of foveal avascular zone in diabetic retinopathy color fundus images
topic RE Ophthalmology
QA75 Electronic computers. Computer science
url http://scholars.utp.edu.my/id/eprint/3181/
http://scholars.utp.edu.my/id/eprint/3181/1/IJMEI_-_Area_Analysis_of_FAZ_new1.pdf