Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopat...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Medicine, UKM Medical Centre
2016
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| Online Access: | http://journalarticle.ukm.my/9841/ http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf |
| _version_ | 1848812201697083392 |
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| author | Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, |
| author_facet | Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, |
| author_sort | Lee, CL |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery. |
| first_indexed | 2025-11-14T23:58:32Z |
| format | Article |
| id | oai:generic.eprints.org:9841 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:58:32Z |
| publishDate | 2016 |
| publisher | Faculty of Medicine, UKM Medical Centre |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:98412016-12-14T06:51:00Z http://journalarticle.ukm.my/9841/ Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery. Faculty of Medicine, UKM Medical Centre 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf Lee, CL and Aini Amelia Zainuddin, and Abdul Kadir Abdul Karim, and Yulianty Arifuddin, and Law, Zhee Kang and Md. Isa N, and Nor Azlin Mohamed Ismail, (2016) Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis. Journal of Surgical Academia, 6 (1). pp. 66-69. ISSN 2231-7481 http://jsurgacad.com/toc/6/1 |
| spellingShingle | Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
| title | Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
| title_full | Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
| title_fullStr | Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
| title_full_unstemmed | Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
| title_short | Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
| title_sort | anti n-methyl-d-aspartate receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
| url | http://journalarticle.ukm.my/9841/ http://journalarticle.ukm.my/9841/ http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf |