Malaysian nasal polyps: eosinophil or neutrophil-predominant
Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Fakulti Perubatan, UKM
2016
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| Online Access: | http://journalarticle.ukm.my/9788/ http://journalarticle.ukm.my/9788/1/8._Syuhada_et_al..pdf |
| _version_ | 1848812187200520192 |
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| author | Syuhada O, Shalini P, Lim, WK Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain, |
| author_facet | Syuhada O, Shalini P, Lim, WK Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain, |
| author_sort | Syuhada O, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data was recorded. The histological slides were retrieved. The number of eosinophils and non-eosinophils were counted and average number of inflammatory cells for each high power field was calculated. Eosinophil-predominant was seen in 32.8% of patients and 67.2% was non-eosinophil-predominant. Phenotypes of NP significantly showed an association with ethnicity (x² = 8.322; p < 0.05). A total of 78.9% of Chinese nasal polyps showed non-eosinophil predominant, while Malay and Indian nasal polyps revealed 71.9% and 40.7% of non-eosinophilic phenotype, respectively. Our study showed that Malaysian population had a non-eosinophilic phenotype of nasal polyps. There was a significant association in Malaysian ethnicity with the highest percentage in Chinese population. |
| first_indexed | 2025-11-14T23:58:18Z |
| format | Article |
| id | oai:generic.eprints.org:9788 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:58:18Z |
| publishDate | 2016 |
| publisher | Fakulti Perubatan, UKM |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:97882016-12-14T06:50:50Z http://journalarticle.ukm.my/9788/ Malaysian nasal polyps: eosinophil or neutrophil-predominant Syuhada O, Shalini P, Lim, WK Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain, Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data was recorded. The histological slides were retrieved. The number of eosinophils and non-eosinophils were counted and average number of inflammatory cells for each high power field was calculated. Eosinophil-predominant was seen in 32.8% of patients and 67.2% was non-eosinophil-predominant. Phenotypes of NP significantly showed an association with ethnicity (x² = 8.322; p < 0.05). A total of 78.9% of Chinese nasal polyps showed non-eosinophil predominant, while Malay and Indian nasal polyps revealed 71.9% and 40.7% of non-eosinophilic phenotype, respectively. Our study showed that Malaysian population had a non-eosinophilic phenotype of nasal polyps. There was a significant association in Malaysian ethnicity with the highest percentage in Chinese population. Fakulti Perubatan, UKM 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9788/1/8._Syuhada_et_al..pdf Syuhada O, and Shalini P, and Lim, WK and Ammar A, and Suria Hayati Md Pauzi, and Aneeza Khairiyah Wan Hamizan, and Balwant Singh Gendeh, and Noraidah Masir, and Salina Husain, (2016) Malaysian nasal polyps: eosinophil or neutrophil-predominant. Medicine & Health, 11 (1). pp. 56-61. ISSN 1823-2140 http://www.medicineandhealthukm.com/toc/11/1 |
| spellingShingle | Syuhada O, Shalini P, Lim, WK Ammar A, Suria Hayati Md Pauzi, Aneeza Khairiyah Wan Hamizan, Balwant Singh Gendeh, Noraidah Masir, Salina Husain, Malaysian nasal polyps: eosinophil or neutrophil-predominant |
| title | Malaysian nasal polyps: eosinophil or neutrophil-predominant |
| title_full | Malaysian nasal polyps: eosinophil or neutrophil-predominant |
| title_fullStr | Malaysian nasal polyps: eosinophil or neutrophil-predominant |
| title_full_unstemmed | Malaysian nasal polyps: eosinophil or neutrophil-predominant |
| title_short | Malaysian nasal polyps: eosinophil or neutrophil-predominant |
| title_sort | malaysian nasal polyps: eosinophil or neutrophil-predominant |
| url | http://journalarticle.ukm.my/9788/ http://journalarticle.ukm.my/9788/ http://journalarticle.ukm.my/9788/1/8._Syuhada_et_al..pdf |