Simulations of hirschsprung’s disease using fractional differential equations

In this paper, we examined a model of cell invasion focusing on the wavefront of the neural crest (NC) cells in the case of Hirschsprung’s disease (HSCR). Hirschsprung’s disease (HSCR) is a congenital defect of intestinal ganglion cells and causes patients to have disorders in peristalsis. This simu...

Full description

Bibliographic Details
Main Author: Abdullah, F.A.
Format: Article
Language:English
Published: Universiti Kebangsaan Malaysia 2013
Online Access:http://journalarticle.ukm.my/6161/
http://journalarticle.ukm.my/6161/1/15_F.A._Abdullah.pdf
_version_ 1848811062993879040
author Abdullah, F.A.
author_facet Abdullah, F.A.
author_sort Abdullah, F.A.
building UKM Institutional Repository
collection Online Access
description In this paper, we examined a model of cell invasion focusing on the wavefront of the neural crest (NC) cells in the case of Hirschsprung’s disease (HSCR). Hirschsprung’s disease (HSCR) is a congenital defect of intestinal ganglion cells and causes patients to have disorders in peristalsis. This simulation model was performed using the fractional differential equations (FDEs) based upon two basic cell functions. Here, we simulated the mathematical model in a one-dimensional setting, based on the fractional trapezoidal numerical scheme and the results showed an interesting outcome for the mobility of the cellular processes under crowded environments.
first_indexed 2025-11-14T23:40:26Z
format Article
id oai:generic.eprints.org:6161
institution Universiti Kebangasaan Malaysia
institution_category Local University
language English
last_indexed 2025-11-14T23:40:26Z
publishDate 2013
publisher Universiti Kebangsaan Malaysia
recordtype eprints
repository_type Digital Repository
spelling oai:generic.eprints.org:61612016-12-14T06:40:31Z http://journalarticle.ukm.my/6161/ Simulations of hirschsprung’s disease using fractional differential equations Abdullah, F.A. In this paper, we examined a model of cell invasion focusing on the wavefront of the neural crest (NC) cells in the case of Hirschsprung’s disease (HSCR). Hirschsprung’s disease (HSCR) is a congenital defect of intestinal ganglion cells and causes patients to have disorders in peristalsis. This simulation model was performed using the fractional differential equations (FDEs) based upon two basic cell functions. Here, we simulated the mathematical model in a one-dimensional setting, based on the fractional trapezoidal numerical scheme and the results showed an interesting outcome for the mobility of the cellular processes under crowded environments. Universiti Kebangsaan Malaysia 2013-05 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/6161/1/15_F.A._Abdullah.pdf Abdullah, F.A. (2013) Simulations of hirschsprung’s disease using fractional differential equations. Sains Malaysiana, 42 (5). pp. 661-666. ISSN 0126-6039 http://www.ukm.my/jsm/
spellingShingle Abdullah, F.A.
Simulations of hirschsprung’s disease using fractional differential equations
title Simulations of hirschsprung’s disease using fractional differential equations
title_full Simulations of hirschsprung’s disease using fractional differential equations
title_fullStr Simulations of hirschsprung’s disease using fractional differential equations
title_full_unstemmed Simulations of hirschsprung’s disease using fractional differential equations
title_short Simulations of hirschsprung’s disease using fractional differential equations
title_sort simulations of hirschsprung’s disease using fractional differential equations
url http://journalarticle.ukm.my/6161/
http://journalarticle.ukm.my/6161/
http://journalarticle.ukm.my/6161/1/15_F.A._Abdullah.pdf