Positive TPMT genotype-phenotype correlation underscores importance of TPMT genotyping for personalized thiopurine dosing

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Positive TPMT genotype-phenotype correlation underscores importance of TPMT genotyping for personalized thiopurine dosing

This study explored TPMT genotype-phenotype correlation in a group of acute lymphoblastic leukemia (ALL) patients to investigate the potential of TPMT genotyping for personalized thiopurine dosing. Genotyping for G238C (TPMT*2), G460A (TPMT*3B) and A719G (TPMT*3C) loci was determined in 89 subjects...

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Bibliographic Details
Main Authors:	Hui-min, Neoh, Mee, Lee Looi, Muhiddin Ishak, Mohd Ridhwan Abd Razak, Noor Hamidah Hussin, Zarina Latiff, Hamidah Alias, Rahman Jamal
Format:	Article
Language:	English
Published:	Penerbit UKM 2012
Online Access:	http://journalarticle.ukm.my/6092/ http://journalarticle.ukm.my/6092/1/2011-1-17.pdf

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