Divalent cations (Mg2+, Ca2+) protect bacterial outer membrane damage by polymyxin B

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Divalent cations (Mg2+, Ca2+) protect bacterial outer membrane damage by polymyxin B

Polymyxin B interacts with divalent cations by displacing cations from their binding sites in the lipopolysaccharide (LPS) molecules. It leads to the disorganization of the outer membrane component of the Gram negative bacteria, which releases LPS component from bacterial surface causing severe memb...

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Bibliographic Details
Main Authors:	Ahmad Zorin Sahalan, Abdul Hamid Abd. Aziz, Hing, Hiang Lian, Mohd Kamel Abd. Ghani
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2013
Online Access:	http://journalarticle.ukm.my/5972/ http://journalarticle.ukm.my/5972/1/05%2520Ahmad%2520Zorin.pdf

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