Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats
This study evaluated four different doses of Strobilanthes crispa juice (700, 2100, 3500 and 4900 mg kg-1 of body weight) administered orally to normal female and male Sprague dawley rats on possible changes in various physical, behaviour, morphology and biochemical parameter. The rats were treated...
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| Format: | Article |
| Language: | English |
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Universiti Kebangsaan Malaysia
2012
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| Online Access: | http://journalarticle.ukm.my/3928/ http://journalarticle.ukm.my/3928/1/03%2520N.A.%2520Norfarizan.pdf |
| _version_ | 1848810349779746816 |
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| author | Norfarizan-Hanoon, N.A Asmah, R Fauziah, O Rokiah, M.Y Faridah, H |
| author_facet | Norfarizan-Hanoon, N.A Asmah, R Fauziah, O Rokiah, M.Y Faridah, H |
| author_sort | Norfarizan-Hanoon, N.A |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | This study evaluated four different doses of Strobilanthes crispa juice (700, 2100, 3500 and 4900 mg kg-1 of body weight) administered orally to normal female and male Sprague dawley rats on possible changes in various physical, behaviour, morphology and biochemical parameter. The rats were treated with a single dose of juice and observed for 14 days. No significant toxicity was observed with respect to clinical parameters and organ morphology. In addition, no significant changes were observed in the level of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, creatinine and albumin. The S. crispus juice was found to be safe at the maximum dose used in this study (4900 mg kg-1 of body weight). |
| first_indexed | 2025-11-14T23:29:06Z |
| format | Article |
| id | oai:generic.eprints.org:3928 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:29:06Z |
| publishDate | 2012 |
| publisher | Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:39282016-12-14T06:35:20Z http://journalarticle.ukm.my/3928/ Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats Norfarizan-Hanoon, N.A Asmah, R Fauziah, O Rokiah, M.Y Faridah, H This study evaluated four different doses of Strobilanthes crispa juice (700, 2100, 3500 and 4900 mg kg-1 of body weight) administered orally to normal female and male Sprague dawley rats on possible changes in various physical, behaviour, morphology and biochemical parameter. The rats were treated with a single dose of juice and observed for 14 days. No significant toxicity was observed with respect to clinical parameters and organ morphology. In addition, no significant changes were observed in the level of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, creatinine and albumin. The S. crispus juice was found to be safe at the maximum dose used in this study (4900 mg kg-1 of body weight). Universiti Kebangsaan Malaysia 2012-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/3928/1/03%2520N.A.%2520Norfarizan.pdf Norfarizan-Hanoon, N.A and Asmah, R and Fauziah, O and Rokiah, M.Y and Faridah, H (2012) Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats. Sains Malaysiana, 41 (4). pp. 403-409. ISSN 0126-6039 http://www.ukm.my/jsm/ |
| spellingShingle | Norfarizan-Hanoon, N.A Asmah, R Fauziah, O Rokiah, M.Y Faridah, H Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats |
| title | Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats |
| title_full | Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats |
| title_fullStr | Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats |
| title_full_unstemmed | Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats |
| title_short | Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats |
| title_sort | absence of toxicity of strobilanthes crispajuice in acute oral toxicity study in sprague dawley rats |
| url | http://journalarticle.ukm.my/3928/ http://journalarticle.ukm.my/3928/ http://journalarticle.ukm.my/3928/1/03%2520N.A.%2520Norfarizan.pdf |