DNA repair at the gene level in trichothiodystrophy cells

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DNA repair at the gene level in trichothiodystrophy cells

Cells from trichothiodystrophy (TTD) group 3 patients are non-hypersensitive to uv irradiation. These cells perform normal genome repair of pyrimidine dimers but fail to excise 6-4 photoproducts and concomitantly, are unable to restore RNA synthesis levels following uv irradiation. This pointed to a...

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Bibliographic Details
Main Authors:	Nathan , Sheila, Mayne, Lynne
Format:	Article
Published:	Universiti Kebangsaan Malaysia 2000
Online Access:	http://journalarticle.ukm.my/3779/

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