The comparative study of Nasopharyngeal Carcinoma incidence and mortality in Malaysia and Thailand: a systematic review
Nasopharyngeal Carcinoma (NPC) is characterized by a distinct geographical distribution and is particularly prevalent in East and Southeast Asia. For further studies and better planning in the future, it is vital to have knowledge about the ecological parameters, including incidence, mortality a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2025
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| Online Access: | http://journalarticle.ukm.my/25887/ http://journalarticle.ukm.my/25887/1/Sains_Kesihatan_23_1_2.pdf |
| Summary: | Nasopharyngeal Carcinoma (NPC) is characterized by a distinct geographical distribution and is particularly
prevalent in East and Southeast Asia. For further studies and better planning in the future, it is vital to have
knowledge about the ecological parameters, including incidence, mortality and so on. The objective of this
study is to analyze the trend of incidence and mortality of nasopharyngeal carcinoma (NPC) cases over time
in Malaysia and Thailand and to offer a comprehensive understanding of the epidemiological patterns of NPC
in Malaysia and Thailand, considering both the unique characteristics and shared features of the disease in
these two nations. A systematic review was conducted. We searched the literature databases of PubMed, MOH,
IntechOpen, SpringerLink and UI Scholars Hub for empirical studies examining the prevalence of NPC cases in
Malaysia and Thailand between 2010 and 2022, which were restricted to studies written in English. Nine studies
were included, which are three retrospective studies, two ecological studies, three descriptive studies and one
narrative review study. The studies show that the inconsistent pattern of NPC cases from 2012 to 2022 suggests
that the incidence of NPC fluctuated in both countries throughout this time. Furthermore, it was discovered that
Thailand’s mortality trend was erratic, exhibiting both rises and falls. Nonetheless, it was found that Malaysia’s
mortality rate was steadily rising. This is aligned with the increase in mortality rates, particularly in the Southeast
Asian region and how the Human Development Index (HDI) is involved in these studies. |
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