Predictive factors for diabetes mellitus: insights from complete blood count analysis
The 10th edition of the International Diabetes Federation reports that 537 million people worldwide had diabetes in 2021. In Southeast Asia, countries like Malaysia are facing a growing burden of diabetes. This highlights the urgent need for innovative and resourceful approaches to diabetes manageme...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2024
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| Online Access: | http://journalarticle.ukm.my/24818/ http://journalarticle.ukm.my/24818/1/SMS%2025.pdf |
| _version_ | 1848816196589191168 |
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| author | Agnes Ayang Kenyang, Nurliyana Juhan, Yong Zulina Zubairi, Nornazirah Azizan, Ho, Chong Mun |
| author_facet | Agnes Ayang Kenyang, Nurliyana Juhan, Yong Zulina Zubairi, Nornazirah Azizan, Ho, Chong Mun |
| author_sort | Agnes Ayang Kenyang, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | The 10th edition of the International Diabetes Federation reports that 537 million people worldwide had diabetes in 2021. In Southeast Asia, countries like Malaysia are facing a growing burden of diabetes. This highlights the urgent need for innovative and resourceful approaches to diabetes management. As the prevalence of diabetes continues to rise in these countries, tailored strategies are necessary. To identify and evaluate the potential prognostic indicators for diabetes mellitus, this study involved a dataset consisting of 500 entries, comprising demographic information and selected blood cells from the Complete Blood Count (CBC) test results obtained from the Clinical Laboratory Faculty of Medicine & Health Sciences, Universiti Malaysia Sabah. Using univariate and multivariate logistic regression analysis, the prognostic predictors for diabetes mellitus were identified. In the univariate analysis, all variables are statistically significance at 5% level of significance. However, at multivariate analysis, only age, mean corpuscular hemoglobin concentration (MCHC), white blood cells (WBC) and hematocrit (HCT) emerged as significant predictors of diabetes mellitus. Notably, the abnormal level in WBC exhibited the greatest association with diabetes mellitus, reflecting a 114.7% increased risk compared to a normal WBC level. The statistic value obtained from Hosmer-Lemeshow was 0.944 indicating a well-fitting model. Additionally, the receiver operator characteristic (ROC) curve has a value of 0.7, indicating a strong performance of the model. In conclusion, CBC parameters can be accurate markers and useful in assisting clinical decision-making when properly applied and interpreted. |
| first_indexed | 2025-11-15T01:02:02Z |
| format | Article |
| id | oai:generic.eprints.org:24818 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T01:02:02Z |
| publishDate | 2024 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:248182025-02-06T02:20:49Z http://journalarticle.ukm.my/24818/ Predictive factors for diabetes mellitus: insights from complete blood count analysis Agnes Ayang Kenyang, Nurliyana Juhan, Yong Zulina Zubairi, Nornazirah Azizan, Ho, Chong Mun The 10th edition of the International Diabetes Federation reports that 537 million people worldwide had diabetes in 2021. In Southeast Asia, countries like Malaysia are facing a growing burden of diabetes. This highlights the urgent need for innovative and resourceful approaches to diabetes management. As the prevalence of diabetes continues to rise in these countries, tailored strategies are necessary. To identify and evaluate the potential prognostic indicators for diabetes mellitus, this study involved a dataset consisting of 500 entries, comprising demographic information and selected blood cells from the Complete Blood Count (CBC) test results obtained from the Clinical Laboratory Faculty of Medicine & Health Sciences, Universiti Malaysia Sabah. Using univariate and multivariate logistic regression analysis, the prognostic predictors for diabetes mellitus were identified. In the univariate analysis, all variables are statistically significance at 5% level of significance. However, at multivariate analysis, only age, mean corpuscular hemoglobin concentration (MCHC), white blood cells (WBC) and hematocrit (HCT) emerged as significant predictors of diabetes mellitus. Notably, the abnormal level in WBC exhibited the greatest association with diabetes mellitus, reflecting a 114.7% increased risk compared to a normal WBC level. The statistic value obtained from Hosmer-Lemeshow was 0.944 indicating a well-fitting model. Additionally, the receiver operator characteristic (ROC) curve has a value of 0.7, indicating a strong performance of the model. In conclusion, CBC parameters can be accurate markers and useful in assisting clinical decision-making when properly applied and interpreted. Penerbit Universiti Kebangsaan Malaysia 2024 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/24818/1/SMS%2025.pdf Agnes Ayang Kenyang, and Nurliyana Juhan, and Yong Zulina Zubairi, and Nornazirah Azizan, and Ho, Chong Mun (2024) Predictive factors for diabetes mellitus: insights from complete blood count analysis. Sains Malaysiana, 53 (10). pp. 3535-3543. ISSN 0126-6039 https://www.ukm.my/jsm/english_journals/vol53num10_2024/contentsVol53num10_2024.html |
| spellingShingle | Agnes Ayang Kenyang, Nurliyana Juhan, Yong Zulina Zubairi, Nornazirah Azizan, Ho, Chong Mun Predictive factors for diabetes mellitus: insights from complete blood count analysis |
| title | Predictive factors for diabetes mellitus: insights from complete blood count analysis |
| title_full | Predictive factors for diabetes mellitus: insights from complete blood count analysis |
| title_fullStr | Predictive factors for diabetes mellitus: insights from complete blood count analysis |
| title_full_unstemmed | Predictive factors for diabetes mellitus: insights from complete blood count analysis |
| title_short | Predictive factors for diabetes mellitus: insights from complete blood count analysis |
| title_sort | predictive factors for diabetes mellitus: insights from complete blood count analysis |
| url | http://journalarticle.ukm.my/24818/ http://journalarticle.ukm.my/24818/ http://journalarticle.ukm.my/24818/1/SMS%2025.pdf |