RAD50 deficiency and its effects on zebrafish embryonic development and DNA repair mechanisms

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RAD50 deficiency and its effects on zebrafish embryonic development and DNA repair mechanisms

The MRE11-RAD50-NBS1 (MRN) complex is essential in detecting, signaling, and repairing DNA double-strand breaks (DSBs), thus maintaining genomic integrity. Mutations in RAD50 are linked to severe conditions such as microcephaly, mental retardation, and growth retardation in humans. This study invest...

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Bibliographic Details
Main Authors:	Nahid Khalili, Shazrul Fazry, Mahmood, Ibrahim, Ahmed Najm, Ahmad Azfaralariff
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2024
Online Access:	http://journalarticle.ukm.my/24752/ http://journalarticle.ukm.my/24752/1/MAE%204.pdf

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