The effects of different solubilizing agents on the transport and pharmacokinetic profiles of indomethacin: in vitro and in vivo approach

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The effects of different solubilizing agents on the transport and pharmacokinetic profiles of indomethacin: in vitro and in vivo approach

The poor water solubility of new chemical entities (NCEs) discovered in pharmaceutical screening programs hampers their development and limits effective treatment delivery. Solubilizing agents offer a direct approach to increase solubility and oral bioavailability. This study employed indomethacin a...

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Bibliographic Details
Main Authors:	Siti Aisyah Zainuddin, Abdul Latip Ab Hamid, Aqila Iman Rafandi, Mashani Mohamad, Khuriah Abdul Hamid, Syed Haroon Khalid
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2024
Online Access:	http://journalarticle.ukm.my/24653/ http://journalarticle.ukm.my/24653/1/SS%2017.pdf

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