Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis

Reviews about early interventions, which are important in stroke rehabilitation due to significant neural plasticity, are relatively less. This study objective was to investigate the effectiveness of different interventions started within one-month post-stroke in improving lower extremity-related ou...

Full description

Bibliographic Details
Main Authors: Yeo Yh, Razali Mf, Ripin Zm, Ridzwan Miz
Format: Article
Language:English
Published: Penerbit UKM 2023
Online Access:http://journalarticle.ukm.my/24391/
http://journalarticle.ukm.my/24391/1/MH_3pdf_.pdf
_version_ 1848816091085668352
author Yeo Yh,
Razali Mf,
Ripin Zm,
Ridzwan Miz,
author_facet Yeo Yh,
Razali Mf,
Ripin Zm,
Ridzwan Miz,
author_sort Yeo Yh,
building UKM Institutional Repository
collection Online Access
description Reviews about early interventions, which are important in stroke rehabilitation due to significant neural plasticity, are relatively less. This study objective was to investigate the effectiveness of different interventions started within one-month post-stroke in improving lower extremity-related outcomes as compared to conventional rehabilitation and the corresponding effectiveness ranking. Cochrane Library, Ovid, PubMed, and Scopus were searched for articles dated up to 18 March 2022. Randomised controlled trials were included if they evaluated the effectiveness of two or more different non-drug, non-invasive, and non-surgical interventions which were started within one-month post-stroke on lower extremity-related outcomes. Network meta-analysis revealed that transcranial direct current stimulation, repetitive transcranial magnetic stimulation, mirror therapy, cycling, transcutaneous auricular vagus nerve stimulation, neuromuscular electrical stimulation (NMES), combination of robot and NMES, and thermal stimulation were significantly more effective in improving lower extremity motor function than conventional rehabilitation. In improving mobility, mirror therapy, cycling, and thermal stimulation were significantly more effective. In enhancing balance, physio ball, transcutaneous electrical nerve stimulation, cycling, thermal stimulation, and robot showed significantly higher effectiveness. Thermal stimulation scored the highest effectiveness ranking in improving lower extremity motor function and mobility whereas robot and backward walking achieved the highest effectiveness ranking in improving balance and gait speed respectively.
first_indexed 2025-11-15T01:00:21Z
format Article
id oai:generic.eprints.org:24391
institution Universiti Kebangasaan Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T01:00:21Z
publishDate 2023
publisher Penerbit UKM
recordtype eprints
repository_type Digital Repository
spelling oai:generic.eprints.org:243912024-10-15T03:20:01Z http://journalarticle.ukm.my/24391/ Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis Yeo Yh, Razali Mf, Ripin Zm, Ridzwan Miz, Reviews about early interventions, which are important in stroke rehabilitation due to significant neural plasticity, are relatively less. This study objective was to investigate the effectiveness of different interventions started within one-month post-stroke in improving lower extremity-related outcomes as compared to conventional rehabilitation and the corresponding effectiveness ranking. Cochrane Library, Ovid, PubMed, and Scopus were searched for articles dated up to 18 March 2022. Randomised controlled trials were included if they evaluated the effectiveness of two or more different non-drug, non-invasive, and non-surgical interventions which were started within one-month post-stroke on lower extremity-related outcomes. Network meta-analysis revealed that transcranial direct current stimulation, repetitive transcranial magnetic stimulation, mirror therapy, cycling, transcutaneous auricular vagus nerve stimulation, neuromuscular electrical stimulation (NMES), combination of robot and NMES, and thermal stimulation were significantly more effective in improving lower extremity motor function than conventional rehabilitation. In improving mobility, mirror therapy, cycling, and thermal stimulation were significantly more effective. In enhancing balance, physio ball, transcutaneous electrical nerve stimulation, cycling, thermal stimulation, and robot showed significantly higher effectiveness. Thermal stimulation scored the highest effectiveness ranking in improving lower extremity motor function and mobility whereas robot and backward walking achieved the highest effectiveness ranking in improving balance and gait speed respectively. Penerbit UKM 2023 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/24391/1/MH_3pdf_.pdf Yeo Yh, and Razali Mf, and Ripin Zm, and Ridzwan Miz, (2023) Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis. Medicine & Health, 18 (2). pp. 328-372. ISSN 1823-2140 https://medicineandhealthukm.com/toc/18/2
spellingShingle Yeo Yh,
Razali Mf,
Ripin Zm,
Ridzwan Miz,
Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis
title Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis
title_full Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis
title_fullStr Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis
title_full_unstemmed Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis
title_short Effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis
title_sort effectiveness of rehabilitative interventions beginning within the first month of stroke onset in improving lower extremity-related outcomes: a systematic review and network meta-analysis
url http://journalarticle.ukm.my/24391/
http://journalarticle.ukm.my/24391/
http://journalarticle.ukm.my/24391/1/MH_3pdf_.pdf