A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography
Parabens, commonly used preservatives in food, cosmetics, and pharmaceutical items, inhibit harmful germ growth. Deep Eutectic Solvents (DES) are intriguing for analyte extraction due to superior properties formed through hydrogen bond acceptors and donor interactions. However, the studies on the op...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2024
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| Online Access: | http://journalarticle.ukm.my/23919/ http://journalarticle.ukm.my/23919/1/SE%2010.pdf |
| _version_ | 1848815968097140736 |
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| author | Nurin Farawani Muhamad Yusri, Noorashikin Md Saleh, Tanusha Devi Elan Solan, Muhammad Zulhaziman Mat Salleh, |
| author_facet | Nurin Farawani Muhamad Yusri, Noorashikin Md Saleh, Tanusha Devi Elan Solan, Muhammad Zulhaziman Mat Salleh, |
| author_sort | Nurin Farawani Muhamad Yusri, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Parabens, commonly used preservatives in food, cosmetics, and pharmaceutical items, inhibit harmful germ growth. Deep Eutectic Solvents (DES) are intriguing for analyte extraction due to superior properties formed through hydrogen bond acceptors and donor interactions. However, the studies on the optimal DES-based extraction conditions for paraben-containing cosmetics and the accuracy of ‘paraben-free’ labels are limited. The most effective DES (DL-Menthol and decanoic acid, 1:2 molar ratio) was applied to cosmetic samples after heating at 80 °C following optimization parameters. FTIR study confirmed hydrogen bonds in DES samples. Both paraben-containing and paraben-free samples showed methyl, ethyl, and propyl paraben peaks from the HPLC analysis. Cosmetic sample paraben concentrations ranged from 0.53 mg/L to 26.08 mg/L (non-spiked). LOD and LOQ were 0.24 mg/L-1.62 mg/L, 0.73 mg/L, and 4.8 mg/L, respectively. Goals were met by establishing a paraben extraction method using DES and investigating paraben quantities in cosmetics. |
| first_indexed | 2025-11-15T00:58:24Z |
| format | Article |
| id | oai:generic.eprints.org:23919 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:58:24Z |
| publishDate | 2024 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:239192024-08-08T08:50:07Z http://journalarticle.ukm.my/23919/ A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography Nurin Farawani Muhamad Yusri, Noorashikin Md Saleh, Tanusha Devi Elan Solan, Muhammad Zulhaziman Mat Salleh, Parabens, commonly used preservatives in food, cosmetics, and pharmaceutical items, inhibit harmful germ growth. Deep Eutectic Solvents (DES) are intriguing for analyte extraction due to superior properties formed through hydrogen bond acceptors and donor interactions. However, the studies on the optimal DES-based extraction conditions for paraben-containing cosmetics and the accuracy of ‘paraben-free’ labels are limited. The most effective DES (DL-Menthol and decanoic acid, 1:2 molar ratio) was applied to cosmetic samples after heating at 80 °C following optimization parameters. FTIR study confirmed hydrogen bonds in DES samples. Both paraben-containing and paraben-free samples showed methyl, ethyl, and propyl paraben peaks from the HPLC analysis. Cosmetic sample paraben concentrations ranged from 0.53 mg/L to 26.08 mg/L (non-spiked). LOD and LOQ were 0.24 mg/L-1.62 mg/L, 0.73 mg/L, and 4.8 mg/L, respectively. Goals were met by establishing a paraben extraction method using DES and investigating paraben quantities in cosmetics. Penerbit Universiti Kebangsaan Malaysia 2024 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/23919/1/SE%2010.pdf Nurin Farawani Muhamad Yusri, and Noorashikin Md Saleh, and Tanusha Devi Elan Solan, and Muhammad Zulhaziman Mat Salleh, (2024) A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography. Sains Malaysiana, 53 (4). pp. 851-868. ISSN 0126-6039 https://www.ukm.my/jsm/english_journals/vol53num4_2024/contentsVol53num4_2024.html |
| spellingShingle | Nurin Farawani Muhamad Yusri, Noorashikin Md Saleh, Tanusha Devi Elan Solan, Muhammad Zulhaziman Mat Salleh, A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography |
| title | A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography |
| title_full | A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography |
| title_fullStr | A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography |
| title_full_unstemmed | A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography |
| title_short | A vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography |
| title_sort | vortex-assisted deep eutectic solvent for parabens extraction in cosmetic samples coupled with high performance liquid chromatography |
| url | http://journalarticle.ukm.my/23919/ http://journalarticle.ukm.my/23919/ http://journalarticle.ukm.my/23919/1/SE%2010.pdf |