Thymoquinone reverses homocysteine-induced endothelial dysfunction via inhibition of endoplasmic reticulum-stress induced oxidative stress pathway
Hyperhomocysteinemia causes endoplasmic reticulum (ER) stress, which elevates reactive oxygen species (ROS) and induces endothelial dysfunction, the hallmark of cardiovascular diseases. Nigella sativa seeds contain thymoquinone (TQ), a cardioprotective bioactive component. Nevertheless, research on...
| Main Authors: | Siti Sarah M. Sofiullah, Dharmani Devi Murugan, Suhaila Abd Muid, Wu, Yuan Seng, Nor Hisam Zamakshshari, Quan, Fu Gan, Patrick, Melonney, Norasikin Ab Azis, Sirasanagandla, Srinivasa Rao, Choy, Ker Woon |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2024
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| Online Access: | http://journalarticle.ukm.my/23744/ http://journalarticle.ukm.my/23744/1/SMT%209.pdf |
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