Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review
Drug resistance is the main issue causing the treatment failure of anticancer drugs. This issue has urged researchers to search for new substances from medicinal plants, which are widely reported as the good sources of anticancer agents. Quisqualis indica is a plant belongs to Combretaceae family, k...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2023
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| Online Access: | http://journalarticle.ukm.my/22796/ http://journalarticle.ukm.my/22796/1/SEN%2011.pdf |
| _version_ | 1848815686972866560 |
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| author | Yuan, Seng Wu Felicia, Michelle Lee Rhanye Mac Guad, Fathima Zahraa Ozeer, Appalaraju Velaga, Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Ker, Woon Choy Sze, Meng Lee Subash C.B. Gopinath, Verma, Amita Tze, Pheng Lau |
| author_facet | Yuan, Seng Wu Felicia, Michelle Lee Rhanye Mac Guad, Fathima Zahraa Ozeer, Appalaraju Velaga, Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Ker, Woon Choy Sze, Meng Lee Subash C.B. Gopinath, Verma, Amita Tze, Pheng Lau |
| author_sort | Yuan, Seng Wu |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Drug resistance is the main issue causing the treatment failure of anticancer drugs. This issue has urged researchers to search for new substances from medicinal plants, which are widely reported as the good sources of anticancer agents. Quisqualis indica is a plant belongs to Combretaceae family, known as Rangoon Creeper, which can be found abundantly in tropical countries and distributed profusely as a wild shrub. It has been widely used traditionally and scientifically claimed to process various therapeutic activities. It has recently been reported to possess various potential anticancer activities against different cancers. Looking at its availability in almost all seasons and grow fast, it is an arising source of herbal medicine in the discovery of anticancer drugs economically. Besides, Q. indica is enriched with several secondary metabolites of interest, which are responsible for the positive findings for its anticancer potentials. In this review, we aim to decipher and discuss the anticancer activities of Q. indica crude extracts and isolated phytochemicals as evidenced in preclinical models, as well as the associated molecular mechanisms. More preclinical investigations on its anticancer potentials should be conducted before translation to clinical testing. |
| first_indexed | 2025-11-15T00:53:56Z |
| format | Article |
| id | oai:generic.eprints.org:22796 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:53:56Z |
| publishDate | 2023 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:227962024-01-03T03:54:54Z http://journalarticle.ukm.my/22796/ Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review Yuan, Seng Wu Felicia, Michelle Lee Rhanye Mac Guad, Fathima Zahraa Ozeer, Appalaraju Velaga, Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Ker, Woon Choy Sze, Meng Lee Subash C.B. Gopinath, Verma, Amita Tze, Pheng Lau Drug resistance is the main issue causing the treatment failure of anticancer drugs. This issue has urged researchers to search for new substances from medicinal plants, which are widely reported as the good sources of anticancer agents. Quisqualis indica is a plant belongs to Combretaceae family, known as Rangoon Creeper, which can be found abundantly in tropical countries and distributed profusely as a wild shrub. It has been widely used traditionally and scientifically claimed to process various therapeutic activities. It has recently been reported to possess various potential anticancer activities against different cancers. Looking at its availability in almost all seasons and grow fast, it is an arising source of herbal medicine in the discovery of anticancer drugs economically. Besides, Q. indica is enriched with several secondary metabolites of interest, which are responsible for the positive findings for its anticancer potentials. In this review, we aim to decipher and discuss the anticancer activities of Q. indica crude extracts and isolated phytochemicals as evidenced in preclinical models, as well as the associated molecular mechanisms. More preclinical investigations on its anticancer potentials should be conducted before translation to clinical testing. Penerbit Universiti Kebangsaan Malaysia 2023 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/22796/1/SEN%2011.pdf Yuan, Seng Wu and Felicia, Michelle Lee and Rhanye Mac Guad, and Fathima Zahraa Ozeer, and Appalaraju Velaga, and Vetriselvan Subramaniyan, and Neeraj Kumar Fuloria, and Shivkanya Fuloria, and Ker, Woon Choy and Sze, Meng Lee and Subash C.B. Gopinath, and Verma, Amita and Tze, Pheng Lau (2023) Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review. Sains Malaysiana, 52 (6). pp. 1749-1758. ISSN 0126-6039 https://www.ukm.my/jsm/english_journals/vol52num6_2023/contentsVol52num6_2023.html |
| spellingShingle | Yuan, Seng Wu Felicia, Michelle Lee Rhanye Mac Guad, Fathima Zahraa Ozeer, Appalaraju Velaga, Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Ker, Woon Choy Sze, Meng Lee Subash C.B. Gopinath, Verma, Amita Tze, Pheng Lau Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review |
| title | Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review |
| title_full | Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review |
| title_fullStr | Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review |
| title_full_unstemmed | Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review |
| title_short | Insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of Quisqualis indica: a mini review |
| title_sort | insights on anticancer activities, associated phytochemicals and potential molecular mechanisms of quisqualis indica: a mini review |
| url | http://journalarticle.ukm.my/22796/ http://journalarticle.ukm.my/22796/ http://journalarticle.ukm.my/22796/1/SEN%2011.pdf |