In Vitro and In Silico study on the interaction between apigenin, kaempferoland 4-hydroxybenzoic acid in xanthine oxidase inhibition
Xanthine oxidase (XO) is a biological enzyme that takes part in purine catabolism. It catalyses the conversion of hypoxanthine to xanthine and eventually xanthine to uric acid. The catabolism reaction increases the level of uric acid and subsequently leads to hyperuricemia. Allopurinol is a XO inhib...
| Main Authors: | Chin, Yong Sin, Loh, Khye Er, Wee, Sze Ping, Ong, Ghim Hock |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2023
|
| Online Access: | http://journalarticle.ukm.my/22783/ http://journalarticle.ukm.my/22783/1/SEN%203.pdf |
Similar Items
Xanthine oxidase inhibitory activity by flavonoids from Chrysanthemum morifolium: in vitro and in silico insights
by: Tey, Zi Tong, et al.
Published: (2024)
by: Tey, Zi Tong, et al.
Published: (2024)
Xanthine oxidase inhibitory activity of methanolic extract of Alternanthera sessilis
by: Chong, Sharmaine, et al.
Published: (2020)
by: Chong, Sharmaine, et al.
Published: (2020)
Phytochemical profiling, in vitro and in vivo xanthine oxidase
inhibition and antihyperuricemic activity of Christia vespertilionis leaf
by: Endrini, Susi, et al.
Published: (2023)
by: Endrini, Susi, et al.
Published: (2023)
Phytochemical profiling, in vitro and in vivo xanthine oxidase
inhibition and antihyperuricemic activity of Christia vespertilionis leaf
by: Susi Endrini, Susi Endrini, et al.
Published: (2023)
by: Susi Endrini, Susi Endrini, et al.
Published: (2023)
Phytochemical profiling, in vitro and in vivo xanthine oxidase
inhibition and antihyperuricemic activity of Christia vespertilionis leaf
by: Endrini, Susi, et al.
Published: (2023)
by: Endrini, Susi, et al.
Published: (2023)
Synthesis, biological evaluation and docking studies of aurone derivatives on Xanthine oxidase enzyme
by: Rullah, Kamal, et al.
Published: (2018)
by: Rullah, Kamal, et al.
Published: (2018)
Low inhibition of alpha-glucosidase and xanthine
oxidase activities of ethanol extract of Momordica
charantia fruit
by: Khatib, Alfi, et al.
Published: (2017)
by: Khatib, Alfi, et al.
Published: (2017)
Antioxidant and xanthine oxidase inhibitory activities of persicaria hydropiper.
by: Noor Hashim, Noor Haslinda, et al.
Published: (2013)
by: Noor Hashim, Noor Haslinda, et al.
Published: (2013)
Inhibition of the chemiluminescence and chemotactic activity of phagocytes for
selected Ficus species extract and their lipoxygenase and xanthine oxidase
enzyme inhibitory
by: Shukranul Mawa,, et al.
Published: (2020)
by: Shukranul Mawa,, et al.
Published: (2020)
Purine isosters in design and development of novel xanthin oxidase inhibitors
by: Luna, Giuseppe
Published: (2022)
by: Luna, Giuseppe
Published: (2022)
Chemical profile of xanthine oxidase inhibitor fraction of Persicaria hydropiper
by: Noor Hashim, Noor Haslinda, et al.
Published: (2018)
by: Noor Hashim, Noor Haslinda, et al.
Published: (2018)
Study of melissopalynological, physical and chemical properties, antioxidant and xanthine oxidase inhibition activity of heterotrigona itama honey in Johor, Malaysia
by: Majid, Mahani
Published: (2019)
by: Majid, Mahani
Published: (2019)
Screening of Xanthine Oxidase inhibitor from potential Malaysian medicinal plants
by: Jamal, Parveen, et al.
Published: (2010)
by: Jamal, Parveen, et al.
Published: (2010)
Cytotoxic and xanthine oxidase inhibitory activities of chemical constituents of alphonsea cylindrica king
by: Mhd Bakri, Yuhanis, et al.
Published: (2019)
by: Mhd Bakri, Yuhanis, et al.
Published: (2019)
Xanthine oxidase inhibitory and DPPH radical scavenging
activities of some primulaceae species
by: Norlida Mamat,, et al.
Published: (2014)
by: Norlida Mamat,, et al.
Published: (2014)
Bioaccessibility of apigenin from Mangifera indica (Water Lily var.) during in vitro gastrointestinal digestion
by: Zulkifli, Marina, et al.
Published: (2019)
by: Zulkifli, Marina, et al.
Published: (2019)
Xanthine oxidase inhibitory activity of Pandanus amaryllifolius roxb. / Nur Afira Ahmad Shukor
by: Nur Afira , Ahmad Shukor
Published: (2017)
by: Nur Afira , Ahmad Shukor
Published: (2017)
Xanthine oxidase inhibitory activity from potential Malaysian medicinal plant as remedies for gout
by: Azmi, Saiful, M.N., et al.
Published: (2012)
by: Azmi, Saiful, M.N., et al.
Published: (2012)
Xanthine Oxidase inhibitory activity from potential Malaysian medicinal plants as remedies for gout
by: Azmi, Saiful Mohammad Nizam, et al.
Published: (2010)
by: Azmi, Saiful Mohammad Nizam, et al.
Published: (2010)
Optimization of process parameters for extraction of xanthine oxidase inhibitor (XOI) from lycopersicon esculentum
by: Jamal, Parveen, et al.
Published: (2011)
by: Jamal, Parveen, et al.
Published: (2011)
Computational Studies Of Natural Flavonoids Towards
The Discovery Of A Potential Xanthine Oxidase Inhibitor.
by: Mohammad Alnajjar, Belal Omar
Published: (2008)
by: Mohammad Alnajjar, Belal Omar
Published: (2008)
Optimization of the elicitation process on chrysanthemum indicum cell suspension culture producing xanthine oxidase inhibitor
by: Amid, Azura, et al.
Published: (2009)
by: Amid, Azura, et al.
Published: (2009)
Optimization of process conditions for extraction of xanthine oxidase inhibitor form potential Malaysian medicinal plant
by: Jamal, Parveen, et al.
Published: (2012)
by: Jamal, Parveen, et al.
Published: (2012)
p-Hydroxybenzoic acid synthesis in mycobacterium tuberculosis
by: Stadthagen, Gustavo, et al.
Published: (2005)
by: Stadthagen, Gustavo, et al.
Published: (2005)
Electrochemical biosensing of chilled seafood freshness by xanthine oxidase immobilized on copper-based metal organic framework nanofiber film
by: Wang, Zhipan, et al.
Published: (2019)
by: Wang, Zhipan, et al.
Published: (2019)
Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques
by: Jamal, Parveen, et al.
Published: (2016)
by: Jamal, Parveen, et al.
Published: (2016)
LC-MS-Q-TOF identification of xanthine oxidase inhibitory phytoconstituents from Averrhoa bilimbi leaves
by: Ahmed, Qamar Uddin, et al.
Published: (2018)
by: Ahmed, Qamar Uddin, et al.
Published: (2018)
Screening and optimization of process conditions for extraction of Xanthine Oxidase Inhibitor from potential local medicinal plants
by: Jamal, Parveen, et al.
Published: (2010)
by: Jamal, Parveen, et al.
Published: (2010)
Intestinal permeability and transport of apigenin across caco-2 cell monolayers
by: Zulkifli, Marina, et al.
Published: (2019)
by: Zulkifli, Marina, et al.
Published: (2019)
Studies on xanthine oxidase inhibitory activity of Plumeria rubra Linn flower / Siti Sarwani Putri Mohamed Isa
by: Siti Sarwani Putri , Mohamed Isa
Published: (2017)
by: Siti Sarwani Putri , Mohamed Isa
Published: (2017)
Carica papaya leaves: a novel and safe source of Xanthine Oxidase Inhibitor (XOI) as gout-remission agent
by: Jamal, Parveen, et al.
Published: (2011)
by: Jamal, Parveen, et al.
Published: (2011)
Green synthesis of Chrysanthemum morifolium silver nanoparticles and evaluation of its antibacterial activity
by: Lai, Mun Leong, et al.
Published: (2024)
by: Lai, Mun Leong, et al.
Published: (2024)
Bioactive compounds, antioxidant, xanthine oxidase inhibitory, tyrosinase inhibitory and anti-inflammatory activities of selected agro-industrial by-products
by: Oskoueian, Ehsan, et al.
Published: (2011)
by: Oskoueian, Ehsan, et al.
Published: (2011)
Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants
by: Koo, Hui Miean, et al.
Published: (2001)
by: Koo, Hui Miean, et al.
Published: (2001)
In vitro and in silico evaluations of diarylpentanoid series as a-glucosidase inhibitor
by: Leong, Sze Wei, et al.
Published: (2018)
by: Leong, Sze Wei, et al.
Published: (2018)
In vitro and in silico insights into the soybean 15-lipoxygenase inhibition with a new C-geranylated chalcone-based flavanone
by: Segaran, Raaginie Tamil, et al.
Published: (2025)
by: Segaran, Raaginie Tamil, et al.
Published: (2025)
Preparation of vermicompost from neem leaf and oil palm empty fruit bunch and evaluation of its bioactivity on fruit fly Bactrocera dorsalis hendel
by: Loh, Khye Er
Published: (2013)
by: Loh, Khye Er
Published: (2013)
Molecular dissection and an in-silico approach of a novel gibberellin 20-oxidase gene of Hibiscus cannabinus l.
by: Ab Shukor, Nor Aini, et al.
Published: (2022)
by: Ab Shukor, Nor Aini, et al.
Published: (2022)
Apoptotic mechanism of apigenin and rutin in ER+- breast cancer cells, MCF-7 / Roziana Kamaludin
by: Kamaludin, Roziana
Published: (2015)
by: Kamaludin, Roziana
Published: (2015)
Antiradical and xanthine oxidase inhibitory activity evaluations of Averrhoa bilimbi L. leaves and identification of bioactive constituents through LC-QTOF-MS/MS and molecular docking approach
by: Ahmed, Qamar Uddin, et al.
Published: (2018)
by: Ahmed, Qamar Uddin, et al.
Published: (2018)
Similar Items
-
Xanthine oxidase inhibitory activity by flavonoids from Chrysanthemum morifolium: in vitro and in silico insights
by: Tey, Zi Tong, et al.
Published: (2024) -
Xanthine oxidase inhibitory activity of methanolic extract of Alternanthera sessilis
by: Chong, Sharmaine, et al.
Published: (2020) -
Phytochemical profiling, in vitro and in vivo xanthine oxidase
inhibition and antihyperuricemic activity of Christia vespertilionis leaf
by: Endrini, Susi, et al.
Published: (2023) -
Phytochemical profiling, in vitro and in vivo xanthine oxidase
inhibition and antihyperuricemic activity of Christia vespertilionis leaf
by: Susi Endrini, Susi Endrini, et al.
Published: (2023) -
Phytochemical profiling, in vitro and in vivo xanthine oxidase
inhibition and antihyperuricemic activity of Christia vespertilionis leaf
by: Endrini, Susi, et al.
Published: (2023)