Uncoupling healthspan and lifespan in long lived Daf-2, Pmk-3 and Sgk-1 knockdown Caenorhabditis elegans
Modulation of genes expression in signaling pathways promotes longevity in Caenorhabditis elegans (C. elegans) but it is unclear whether this will improve healthspan. This study aimed to determine the healthspan of daf-2, pmk-3 and sgk-1 knocked-down worms. Health measures were determined at day 5,...
| Main Authors: | Siti Bazilah Zulkefli, Geetha Gunasekaran, Goon Jo Aan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pusat Perubatan Universiti Kebangsaan Malaysia
2022
|
| Online Access: | http://journalarticle.ukm.my/22357/ http://journalarticle.ukm.my/22357/1/Uncoupling%20Healthspan%20and%20Lifespan%20in%20Longlived%20Daf-2%2C%20Pmk-3%20and%20Sgk-1%20Knockdown.pdf |
Similar Items
Effect of the tocotrienol-rich fraction (TRF) on the healthspan of Caenorhabditis elegans
by: Tan, Tzer Sien, et al.
Published: (2021)
by: Tan, Tzer Sien, et al.
Published: (2021)
Toxicology studies in Caenorhabditis elegans
by: Budd, Chloe Denisha
Published: (2008)
by: Budd, Chloe Denisha
Published: (2008)
Spaceflight and ageing: reflecting on Caenorhabditis elegans in space
by: Honda, Y., et al.
Published: (2014)
by: Honda, Y., et al.
Published: (2014)
Caenorhabditis elegans-based analysis of Salmonella enterica
by: Khoo, Chai Hoon, et al.
Published: (2010)
by: Khoo, Chai Hoon, et al.
Published: (2010)
Effects of α-synuclein overexpression in transgenic Caenorhabditis elegans strains
by: Bodhicharla, Rakesh, et al.
Published: (2012)
by: Bodhicharla, Rakesh, et al.
Published: (2012)
Identification of genes conferring resistance to furan in Caenorhabditis elegans
by: Cai, Ning
Published: (2009)
by: Cai, Ning
Published: (2009)
Levels of acid sphingomyelinase (ASM) in Caenorhabditis elegans in microgravity
by: Gravely, Annabel, et al.
Published: (2018)
by: Gravely, Annabel, et al.
Published: (2018)
Characterisation of the effects of the food borne toxicant furan on Caenorhabditis elegans
by: Below, Cristina Catherine
Published: (2011)
by: Below, Cristina Catherine
Published: (2011)
Caenorhabditis elegans stress related gene responses to selected pesticides
by: Antoniou-Kourounioti, Melissa
Published: (2010)
by: Antoniou-Kourounioti, Melissa
Published: (2010)
Expression of the Caenorhabditis elegans aryl hydrocarbon receptor ligand binding domain
by: Helaly, Ahmed
Published: (2011)
by: Helaly, Ahmed
Published: (2011)
Prodigiosin Serratia marcescens tidak bersifat toksik terhadap Caenorhabditis elegans
by: Seah, Siew-Wei, et al.
Published: (2020)
by: Seah, Siew-Wei, et al.
Published: (2020)
Molecular Genetic Analysis of the alpha-latrotoxin Receptor
Latrophilin in the Nematode Caenorhabditis elegans.
by: Mee, Christopher
Published: (2002)
by: Mee, Christopher
Published: (2002)
Electrophiles and Michael acceptors as Nrf2 modulators in a Caenorhabditis elegans model.
by: Lee , Chong Yew
by: Lee , Chong Yew
Phenotypic And Proteomic Analysis Associated With Macrocyclic Lactones-Ivermectin Exposure In Caenorhabditis Elegans
by: Zain, Mariani Mohd
Published: (2019)
by: Zain, Mariani Mohd
Published: (2019)
Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans
models of human neurodegenerative diseases
by: Muñoz-Lobato, Fernando, et al.
Published: (2014)
by: Muñoz-Lobato, Fernando, et al.
Published: (2014)
Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development
by: Mora-Lorca, José Antonio, et al.
Published: (2016)
by: Mora-Lorca, José Antonio, et al.
Published: (2016)
Screening Of Anti Infectives From
Malaysian Marine Organisms
Using Caenorhabditis Elegans
As Model Organism
by: Lee , Wan Ting
Published: (2014)
by: Lee , Wan Ting
Published: (2014)
Analysis of the role of DAF in the uncoating of DAF-binding enteroviruses
by: Williams, David, et al.
Published: (2005)
by: Williams, David, et al.
Published: (2005)
In Vitro Study Of The Efficacy Of Six Ethnoveterinary Plants Species Against Parasitic Nematodes And Caenorhabditis elegans In Nigeria
by: Gagman, Haladu Ali
Published: (2018)
by: Gagman, Haladu Ali
Published: (2018)
Low-intensity microwave irradiation does not substantially alter gene expression in late larval and adult Caenorhabditis elegans.
by: Dawe, Adam S., et al.
Published: (2009)
by: Dawe, Adam S., et al.
Published: (2009)
Predatory behaviour of trapping fungi against srf mutants of Caenorhabditis elegans and different plant and animal parasitic nematodes
by: Mendoza de Gives, P., et al.
Published: (1999)
by: Mendoza de Gives, P., et al.
Published: (1999)
A Marine Actinomycete Rescues Caenorhabditis elegans from Pseudomonas aeruginosa Infection through Restitution of Lysozyme 7
by: Fatin, Siti N., et al.
Published: (2017)
by: Fatin, Siti N., et al.
Published: (2017)
Knockdown of the C. elegans kinome identifies kinases required for normal protein homeostasis, mitochondrial network structure, and sarcomere structure in muscle
by: Lehmann, Susann, et al.
Published: (2013)
by: Lehmann, Susann, et al.
Published: (2013)
A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans
by: Dawe, Adam S., et al.
Published: (2006)
by: Dawe, Adam S., et al.
Published: (2006)
Attachment tests of Pasteuria penetrans to the cuticle of plant and animal parasitic nematodes, free living nematodes and srf mutants of Caenorhabditis elegans
by: Mendoza de Gives, P., et al.
Published: (1999)
by: Mendoza de Gives, P., et al.
Published: (1999)
Laboratory adapted Escherichia coli K-12 becomes a pathogen of Caenorhabditis elegans upon restoration of O antigen biosynthesis
by: Browning, D.F., et al.
Published: (2013)
by: Browning, D.F., et al.
Published: (2013)
Investigating the size-dependent toxicological effects of zinc oxide nanoparticles on Caenorhabditis elegans and the inhibitory potential of Cytochrome P450 isozymes
by: Chowdhury, Lamia Noushin Sadeque
Published: (2024)
by: Chowdhury, Lamia Noushin Sadeque
Published: (2024)
Regional diets targeting gut microbial dynamics to support prolonged healthspan
by: Low, Dorrain Yanwen, et al.
Published: (2021)
by: Low, Dorrain Yanwen, et al.
Published: (2021)
Exploring the effects of medicinal fungi on isolated bladder strips (ex vivo) and Caenorhabditis elegans (in vivo): focus on the caterpillar fungus, Ophiocordyceps sinensis
by: Pang, Li Yin
Published: (2024)
by: Pang, Li Yin
Published: (2024)
The 2014 DAF survey at the University of Sheffield
by: Cox, Andrew, et al.
Published: (2015)
by: Cox, Andrew, et al.
Published: (2015)
Use of transgenic GFP reporter strains of the nematode Caenorhabditis elegans to investigate the patterns of stress responses induced by pesticides and by organic extracts from agricultural soils
by: Anbalagan, Charumathi, et al.
Published: (2013)
by: Anbalagan, Charumathi, et al.
Published: (2013)
Interactions of decay-accelerating factor (DAF) with haemagglutinating human enteroviruses: utilizing variation in primate DAF to map virus binding sites
by: Williams, David, et al.
Published: (2009)
by: Williams, David, et al.
Published: (2009)
The development of occupations across the lifespan
by: Cordier, Reinie, et al.
Published: (2017)
by: Cordier, Reinie, et al.
Published: (2017)
Modal intelektual dan prestasi perniagaan mikro dan kecil (PMK) : sebuah sorotan karya naratif
by: Suraiya Ishak,, et al.
Published: (2022)
by: Suraiya Ishak,, et al.
Published: (2022)
Motor control and coordination across the lifespan
by: Piek, Jan, et al.
Published: (2008)
by: Piek, Jan, et al.
Published: (2008)
Effects of khat ethanol extract, cathinone and cathine on cytochrome P450 activities in vitro, molecular docking CYP-cathinone and CYP-cathine interactions and in vivo effects on Caenorhabditis elegans
by: Lim, Sharoen Yu Ming
Published: (2024)
by: Lim, Sharoen Yu Ming
Published: (2024)
Continuous Wave and simulated GSM exposure at 1.8 W/kg and 1.8 GHz do not induce hsp16-1 heat-shock gene expression in Caenorhabditis elegans
by: Dawe, Adam S., et al.
Published: (2008)
by: Dawe, Adam S., et al.
Published: (2008)
Lifespan perspective theory and (classical) musicians’ careers
by: Bennett, Dawn, et al.
Published: (2018)
by: Bennett, Dawn, et al.
Published: (2018)
Uncoupling the structure–activity relationships of β2 adrenergic receptor ligands from membrane binding
by: Dickson, Callum J., et al.
Published: (2016)
by: Dickson, Callum J., et al.
Published: (2016)
Improvement of cylinder buckling knockdown factor through imperfection sensitivity
by: Ismail, Mohd Shahrom, et al.
Published: (2014)
by: Ismail, Mohd Shahrom, et al.
Published: (2014)
Similar Items
-
Effect of the tocotrienol-rich fraction (TRF) on the healthspan of Caenorhabditis elegans
by: Tan, Tzer Sien, et al.
Published: (2021) -
Toxicology studies in Caenorhabditis elegans
by: Budd, Chloe Denisha
Published: (2008) -
Spaceflight and ageing: reflecting on Caenorhabditis elegans in space
by: Honda, Y., et al.
Published: (2014) -
Caenorhabditis elegans-based analysis of Salmonella enterica
by: Khoo, Chai Hoon, et al.
Published: (2010) -
Effects of α-synuclein overexpression in transgenic Caenorhabditis elegans strains
by: Bodhicharla, Rakesh, et al.
Published: (2012)