Molecular docking analysis on the designed benzimidazole derivatives as EGFR inhibitors: comparison between EGFR wild-type (EGFRWT) and T790M mutant

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Molecular docking analysis on the designed benzimidazole derivatives as EGFR inhibitors: comparison between EGFR wild-type (EGFRWT) and T790M mutant

The non-small cell lung (NSCL) and colorectal cancers are frequently linked with the oncogenic activation of the epidermal growth factor receptor (EGFR), a member of the receptor tyrosine kinase (RTK) family. Current tyrosine kinase inhibitors (TKIs) are susceptible to drug resistance mutations and...

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Bibliographic Details
Main Authors:	Nurul Awani Syazzira Jalil, Shafida Abd Hamid
Format:	Article
Language:	English
Published:	Universiti Kebangsaan Malaysia 2023
Online Access:	http://journalarticle.ukm.my/22069/ http://journalarticle.ukm.my/22069/1/SE%2013.pdf

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