Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles
The synthesis of novel metallic nanoparticles (NPs) using plant materials has emerged as a cost-effective alternative to synthetic NPs and has found wide application in biomedical, cosmetic, bioremediation, and health care technology. This study aimed to synthesize and characterize the morphologies,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universiti Kebangsaan Malaysia
2022
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| Online Access: | http://journalarticle.ukm.my/21018/ http://journalarticle.ukm.my/21018/1/SBL%2012.pdf |
| _version_ | 1848815250355257344 |
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| author | Ter, Boon Siang Sinouvassane Djearamane, Yeoh, Fanne Fern Nii Anto Cordelia Tanislaus Antony Dhanapal, |
| author_facet | Ter, Boon Siang Sinouvassane Djearamane, Yeoh, Fanne Fern Nii Anto Cordelia Tanislaus Antony Dhanapal, |
| author_sort | Ter, Boon Siang |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | The synthesis of novel metallic nanoparticles (NPs) using plant materials has emerged as a cost-effective alternative to synthetic NPs and has found wide application in biomedical, cosmetic, bioremediation, and health care technology. This study aimed to synthesize and characterize the morphologies, functional groups, and crystalline structures of silver nanoparticles (AgNPs) deduced using B. chinense (Bc) and C. chinensis (Cc). The biogenic AgNPs were appraised for their antioxidant content, radical scavenging activities, antimicrobial, anti-inflammatory, and anti-diabetic activities to understand their functional and health promoting properties. The AgNPs deduced from both plants were spherical in shape with the size of 20-30 nm and possessed face centered cubic phase arrangement. The total phenolic content (TPC) was high in Cc-AgNPs (166.2100 mgGAE/g) and exhibited strong hydroxyl (OH-) and ABTS+ radical scavenging activities. On the contrary, Bc-AgNPs with higher TFC (286.1438 mgQE/g) had greater nitric-oxide (NO), DPPH, Fe2+scavenging and anti-albumin denaturation activities. Minimum anti-α-amylase activity disparity was observed between Cc-AgNPs (EC50 = 0.2903 mg/mL) and Bc-AgNPs (EC50 = 0.2975 mg/mL) due to various inhibition mode contributed by bioactive compounds. Besides, Bc-AgNPs showed strongest inhibition towards Gram negative bacteria while Cc-AgNPs was more effective as an antifungal agent. In conclusion, biogenic AgNPs exhibited strong functional and bioactive properties which may be attributed to the presence of bioactive compounds on the surface of AgNPs and further in-depth analysis are required to be used for various biomedical applications. |
| first_indexed | 2025-11-15T00:46:59Z |
| format | Article |
| id | oai:generic.eprints.org:21018 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:46:59Z |
| publishDate | 2022 |
| publisher | Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:210182023-02-01T06:53:18Z http://journalarticle.ukm.my/21018/ Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles Ter, Boon Siang Sinouvassane Djearamane, Yeoh, Fanne Fern Nii Anto Cordelia Tanislaus Antony Dhanapal, The synthesis of novel metallic nanoparticles (NPs) using plant materials has emerged as a cost-effective alternative to synthetic NPs and has found wide application in biomedical, cosmetic, bioremediation, and health care technology. This study aimed to synthesize and characterize the morphologies, functional groups, and crystalline structures of silver nanoparticles (AgNPs) deduced using B. chinense (Bc) and C. chinensis (Cc). The biogenic AgNPs were appraised for their antioxidant content, radical scavenging activities, antimicrobial, anti-inflammatory, and anti-diabetic activities to understand their functional and health promoting properties. The AgNPs deduced from both plants were spherical in shape with the size of 20-30 nm and possessed face centered cubic phase arrangement. The total phenolic content (TPC) was high in Cc-AgNPs (166.2100 mgGAE/g) and exhibited strong hydroxyl (OH-) and ABTS+ radical scavenging activities. On the contrary, Bc-AgNPs with higher TFC (286.1438 mgQE/g) had greater nitric-oxide (NO), DPPH, Fe2+scavenging and anti-albumin denaturation activities. Minimum anti-α-amylase activity disparity was observed between Cc-AgNPs (EC50 = 0.2903 mg/mL) and Bc-AgNPs (EC50 = 0.2975 mg/mL) due to various inhibition mode contributed by bioactive compounds. Besides, Bc-AgNPs showed strongest inhibition towards Gram negative bacteria while Cc-AgNPs was more effective as an antifungal agent. In conclusion, biogenic AgNPs exhibited strong functional and bioactive properties which may be attributed to the presence of bioactive compounds on the surface of AgNPs and further in-depth analysis are required to be used for various biomedical applications. Universiti Kebangsaan Malaysia 2022 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/21018/1/SBL%2012.pdf Ter, Boon Siang and Sinouvassane Djearamane, and Yeoh, Fanne Fern Nii and Anto Cordelia Tanislaus Antony Dhanapal, (2022) Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles. Sains Malaysiana, 51 (11). pp. 3663-3676. ISSN 0126-6039 http://www.ukm.my/jsm/index.html |
| spellingShingle | Ter, Boon Siang Sinouvassane Djearamane, Yeoh, Fanne Fern Nii Anto Cordelia Tanislaus Antony Dhanapal, Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles |
| title | Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles |
| title_full | Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles |
| title_fullStr | Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles |
| title_full_unstemmed | Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles |
| title_short | Functional and bioactive properties of Bupleurum chinense DC. and Clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles |
| title_sort | functional and bioactive properties of bupleurum chinense dc. and clematis chinensis osbeck mediated biogenic synthesized silver nanoparticles |
| url | http://journalarticle.ukm.my/21018/ http://journalarticle.ukm.my/21018/ http://journalarticle.ukm.my/21018/1/SBL%2012.pdf |