Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus
Case of co-existence of twin pregnancy of complete hydatidiform molar with viable intrauterine pregnancy is extremely rare with low incidence of 1 case for 20,000 – 100,000. It is associated with high risk of spontaneous abortion, preterm delivery, intrauterine death, bleeding, pre-eclampsia,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pusat Perubatan Universiti Kebangsaan Malaysia
2018
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| Online Access: | http://journalarticle.ukm.my/20620/ http://journalarticle.ukm.my/20620/1/19_ms0219_pdf_11715.pdf |
| _version_ | 1848815150945009664 |
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| author | Munirah Md Mansor, Khalidah MB, Dian Nasriana Nasuruddin, Hanita O, |
| author_facet | Munirah Md Mansor, Khalidah MB, Dian Nasriana Nasuruddin, Hanita O, |
| author_sort | Munirah Md Mansor, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Case of co-existence of twin pregnancy of complete hydatidiform molar with
viable intrauterine pregnancy is extremely rare with low incidence of 1 case for
20,000 – 100,000. It is associated with high risk of spontaneous abortion, preterm
delivery, intrauterine death, bleeding, pre-eclampsia, and persistence trophoblastic
disease (PTD). It may associate with biochemical derangement that may induce
symptomatic manifestation to the mother. There are few cases reported in Asia
population with significant clinical dilemma and management to the maternal and
foetus. Here, we report a case of a young woman with previous bad obstetric
history who presented with antepartum per-vaginal bleeding and was noted to
have a twin pregnancy with complete hydatidiform molar and viable foetus. It
was complicated with markedly elevated human chorionic gonadotropin (hCG)
and hyperthyroidism. Postpartumly, her hCG level was persistently high and her
condition progressed into gestational trophoblastic neoplasm. |
| first_indexed | 2025-11-15T00:45:25Z |
| format | Article |
| id | oai:generic.eprints.org:20620 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:45:25Z |
| publishDate | 2018 |
| publisher | Pusat Perubatan Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:206202022-11-28T13:11:33Z http://journalarticle.ukm.my/20620/ Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus Munirah Md Mansor, Khalidah MB, Dian Nasriana Nasuruddin, Hanita O, Case of co-existence of twin pregnancy of complete hydatidiform molar with viable intrauterine pregnancy is extremely rare with low incidence of 1 case for 20,000 – 100,000. It is associated with high risk of spontaneous abortion, preterm delivery, intrauterine death, bleeding, pre-eclampsia, and persistence trophoblastic disease (PTD). It may associate with biochemical derangement that may induce symptomatic manifestation to the mother. There are few cases reported in Asia population with significant clinical dilemma and management to the maternal and foetus. Here, we report a case of a young woman with previous bad obstetric history who presented with antepartum per-vaginal bleeding and was noted to have a twin pregnancy with complete hydatidiform molar and viable foetus. It was complicated with markedly elevated human chorionic gonadotropin (hCG) and hyperthyroidism. Postpartumly, her hCG level was persistently high and her condition progressed into gestational trophoblastic neoplasm. Pusat Perubatan Universiti Kebangsaan Malaysia 2018-12 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/20620/1/19_ms0219_pdf_11715.pdf Munirah Md Mansor, and Khalidah MB, and Dian Nasriana Nasuruddin, and Hanita O, (2018) Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus. Medicine & Health, 13 (2). pp. 180-187. ISSN 2289-5728 https://www.medicineandhealthukm.com/toc/13/2 |
| spellingShingle | Munirah Md Mansor, Khalidah MB, Dian Nasriana Nasuruddin, Hanita O, Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus |
| title | Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus |
| title_full | Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus |
| title_fullStr | Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus |
| title_full_unstemmed | Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus |
| title_short | Biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus |
| title_sort | biochemical derangement in twin pregnancy : complete hydatidiform mole and viable foetus |
| url | http://journalarticle.ukm.my/20620/ http://journalarticle.ukm.my/20620/ http://journalarticle.ukm.my/20620/1/19_ms0219_pdf_11715.pdf |